Increased drug resistance of cultured human cancer cell lines in three-dimensional cellular growth assay using collagen gel matrix

We have conducted a three‐dimensional cellular growth assay using collagen gel matrix with an endpoint of the 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyl‐2H tetrazolium bromide (MTT) assay, on four human gastric and colonic cancer cell lines. Three‐dimensionally growing cells in collagen gel matrix we...

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