Endocannabinoids and related fatty acid derivatives in pain modulation

The brain produces at least five compounds that possess sub-micromolar affinity for cannabinoid receptors: anandamide, 2-arachidonoylglycerol, noladin ether, virodhamine, and N-arachidonoyldopamine (NADA). One function of these and/or related compounds is to suppress pain sensitivity. Much evidence...

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Veröffentlicht in:	Chemistry and Physics of Lipids 2002-12, Vol.121 (1), p.159-172
Hauptverfasser:	Walker, J.Michael, Krey, Jocelyn F., Chu, Constance J., Huang, Susan M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesia Anandamide Animals Biomarkers Cannabinoid Cannabinoid Receptor Modulators Endocannabinoid Endocannabinoids Fatty Acids - chemistry Fatty Acids - metabolism Fatty Acids - pharmacology Fatty Acids, Unsaturated - chemistry Fatty Acids, Unsaturated - metabolism Fatty Acids, Unsaturated - pharmacology Humans Nervous System - metabolism Pain Pain - metabolism Receptor Receptors, Cannabinoid Receptors, Drug - metabolism
Online-Zugang:	Volltext
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