Detection of ciprofloxacin resistance in gram-negative bacteria due to alterations in gyrA

Two plasmids containing the cloned Escherichia coli wild-type gyrA gene were used to transform ciprofloxacin-resistant Gram-negative clinical isolates to screen for DNA gyrase A-mediated quinolone resistance. The results show that the technique is simple and applicable to a wide range of Gram-negati...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 1992, Vol.29 (1), p.9-17
Hauptverfasser:	POWER, E. G. M, MUNOZ BELLIDO, J. L, PHILLIPS, I
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriology Biological and medical sciences Ciprofloxacin - pharmacology DNA Topoisomerases, Type II - genetics Drug Resistance, Microbial - genetics Escherichia coli - genetics Fundamental and applied biological sciences. Psychology Genetics Gram-Negative Bacteria - drug effects Gram-Negative Bacteria - genetics Microbiology Plasmids
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