Aftereffects of Exercise on Regional and Systemic Hemodynamics in Hypertension
Several studies have indicated that a single bout of physical exercise induced a significant antihypertensive effect during the hours after the activity. However, little information is presently available on the underlying hemodynamic changes. We examined 13 essential hypertensive patients and nine...
Gespeichert in:
| Veröffentlicht in: | Hypertension (Dallas, Tex. 1979) Tex. 1979), 1992-02, Vol.19 (2), p.183-191 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 191 |
|---|---|
| container_issue | 2 |
| container_start_page | 183 |
| container_title | Hypertension (Dallas, Tex. 1979) |
| container_volume | 19 |
| creator | Cléroux, Jean Kouamé, NʼGuessan Nadeau, André Coulombe, Denis Lacourcière, Yves |
| description | Several studies have indicated that a single bout of physical exercise induced a significant antihypertensive effect during the hours after the activity. However, little information is presently available on the underlying hemodynamic changes. We examined 13 essential hypertensive patients and nine nonnotensive subjects in a randomized, crossover study design during 3 hours after a 30-minute period of upright leg cycling at 50% of peak aerobic capacity and during 3 hours after a 30-minute control period of rest Blood pressure, heart rate, cardiac output, total peripheral resistance, and regional vascular resistance in the forearm as well as venous plasma catecholamine concentrations were measured repeatedly. After exercise, systolic (−11±2 mm Hg) and diastolic (−4±1 mm Hg) blood pressures, total peripheral resistance (−27±5%), forearm vascular resistance (−25±6%), and plasma norepinephrine levels (−21±7%) were significantly (p |
| doi_str_mv | 10.1161/01.hyp.19.2.183 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72797885</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72797885</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5609-52d0fdc1f3d4ddd637db28aaa4ad814d6132ace0aef74e26287dd95a51f67d443</originalsourceid><addsrcrecordid>eNpFkMuLFDEQh4Mo67h69iTkIN66N5Vn57gsqyMsKj5ATyGbVJzWfswmPaz935tlBs2lkqqvfpCPkJfAWgANFwza3bpvwba8hU48IhtQXDZSafGYbBhY2ViA70_Js1J-MQZSSnNGzsAIo5XYkA-XacGMKWFYCp0Tvf6DOfQF6TzRz_iznyc_UD9F-mUtC459oFsc57hOvt4L7Se6XfeYF5xKZZ-TJ8kPBV-c6jn59vb669W2ufn47v3V5U0TlGa2UTyyFAMkEWWMUQsTb3nnvZc-diCjBsF9QOYxGYlc887EaJVXkLSJUopz8uaYu8_z3QHL4sa-BBwGP-F8KM5wY03XqQpeHMGQ51LqR90-96PPqwPmHgw6Bm7745MD67irBuvGq1P04XbE-J8_Kqvz16e5L8EPKfup-vqHKa6YMKxi8ojdz0M1XH4Ph3vMbod-WHaO1SO57hqwljNeX81Dy4q_RLyJhw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72797885</pqid></control><display><type>article</type><title>Aftereffects of Exercise on Regional and Systemic Hemodynamics in Hypertension</title><source>MEDLINE</source><source>American Heart Association Journals</source><source>Journals@Ovid Complete</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Cléroux, Jean ; Kouamé, NʼGuessan ; Nadeau, André ; Coulombe, Denis ; Lacourcière, Yves</creator><creatorcontrib>Cléroux, Jean ; Kouamé, NʼGuessan ; Nadeau, André ; Coulombe, Denis ; Lacourcière, Yves</creatorcontrib><description>Several studies have indicated that a single bout of physical exercise induced a significant antihypertensive effect during the hours after the activity. However, little information is presently available on the underlying hemodynamic changes. We examined 13 essential hypertensive patients and nine nonnotensive subjects in a randomized, crossover study design during 3 hours after a 30-minute period of upright leg cycling at 50% of peak aerobic capacity and during 3 hours after a 30-minute control period of rest Blood pressure, heart rate, cardiac output, total peripheral resistance, and regional vascular resistance in the forearm as well as venous plasma catecholamine concentrations were measured repeatedly. After exercise, systolic (−11±2 mm Hg) and diastolic (−4±1 mm Hg) blood pressures, total peripheral resistance (−27±5%), forearm vascular resistance (−25±6%), and plasma norepinephrine levels (−21±7%) were significantly (p<0.05) decreased, and cardiac output was increased (+31±8%) compared with control in hypertensive subjects. In contrast, in normotensive subjects blood pressure, forearm vascular resistance, and plasma norepinephrine were unchanged, and systemic hemodynamics changed to a lesser extent than in hypertensive subjects after exercise. It is concluded that a decrease in regional vascular resistance in skeletal muscles and possibly in the skin in hypertensive patients may contribute importantly to the antihypertensive effect of prior exercise. A decreased sympathetic nervous activity, as seen from lower plasma norepinephrine levels, may be involved in this effect.</description><identifier>ISSN: 0194-911X</identifier><identifier>EISSN: 1524-4563</identifier><identifier>DOI: 10.1161/01.hyp.19.2.183</identifier><identifier>PMID: 1737653</identifier><identifier>CODEN: HPRTDN</identifier><language>eng</language><publisher>Philadelphia, PA: American Heart Association, Inc</publisher><subject>Adult ; Arterial hypertension. Arterial hypotension ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Clinical manifestations. Epidemiology. Investigative techniques. Etiology ; Exercise ; Female ; Forearm - blood supply ; Heart Rate ; Hemodynamics ; Humans ; Hypertension - blood ; Hypertension - physiopathology ; Male ; Medical sciences ; Norepinephrine - blood ; Random Allocation ; Reference Values ; Regional Blood Flow</subject><ispartof>Hypertension (Dallas, Tex. 1979), 1992-02, Vol.19 (2), p.183-191</ispartof><rights>1992 American Heart Association, Inc.</rights><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5609-52d0fdc1f3d4ddd637db28aaa4ad814d6132ace0aef74e26287dd95a51f67d443</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,780,784,789,790,3687,23930,23931,25140,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=5250370$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1737653$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cléroux, Jean</creatorcontrib><creatorcontrib>Kouamé, NʼGuessan</creatorcontrib><creatorcontrib>Nadeau, André</creatorcontrib><creatorcontrib>Coulombe, Denis</creatorcontrib><creatorcontrib>Lacourcière, Yves</creatorcontrib><title>Aftereffects of Exercise on Regional and Systemic Hemodynamics in Hypertension</title><title>Hypertension (Dallas, Tex. 1979)</title><addtitle>Hypertension</addtitle><description>Several studies have indicated that a single bout of physical exercise induced a significant antihypertensive effect during the hours after the activity. However, little information is presently available on the underlying hemodynamic changes. We examined 13 essential hypertensive patients and nine nonnotensive subjects in a randomized, crossover study design during 3 hours after a 30-minute period of upright leg cycling at 50% of peak aerobic capacity and during 3 hours after a 30-minute control period of rest Blood pressure, heart rate, cardiac output, total peripheral resistance, and regional vascular resistance in the forearm as well as venous plasma catecholamine concentrations were measured repeatedly. After exercise, systolic (−11±2 mm Hg) and diastolic (−4±1 mm Hg) blood pressures, total peripheral resistance (−27±5%), forearm vascular resistance (−25±6%), and plasma norepinephrine levels (−21±7%) were significantly (p<0.05) decreased, and cardiac output was increased (+31±8%) compared with control in hypertensive subjects. In contrast, in normotensive subjects blood pressure, forearm vascular resistance, and plasma norepinephrine were unchanged, and systemic hemodynamics changed to a lesser extent than in hypertensive subjects after exercise. It is concluded that a decrease in regional vascular resistance in skeletal muscles and possibly in the skin in hypertensive patients may contribute importantly to the antihypertensive effect of prior exercise. A decreased sympathetic nervous activity, as seen from lower plasma norepinephrine levels, may be involved in this effect.</description><subject>Adult</subject><subject>Arterial hypertension. Arterial hypotension</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology. Vascular system</subject><subject>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</subject><subject>Exercise</subject><subject>Female</subject><subject>Forearm - blood supply</subject><subject>Heart Rate</subject><subject>Hemodynamics</subject><subject>Humans</subject><subject>Hypertension - blood</subject><subject>Hypertension - physiopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Norepinephrine - blood</subject><subject>Random Allocation</subject><subject>Reference Values</subject><subject>Regional Blood Flow</subject><issn>0194-911X</issn><issn>1524-4563</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMuLFDEQh4Mo67h69iTkIN66N5Vn57gsqyMsKj5ATyGbVJzWfswmPaz935tlBs2lkqqvfpCPkJfAWgANFwza3bpvwba8hU48IhtQXDZSafGYbBhY2ViA70_Js1J-MQZSSnNGzsAIo5XYkA-XacGMKWFYCp0Tvf6DOfQF6TzRz_iznyc_UD9F-mUtC459oFsc57hOvt4L7Se6XfeYF5xKZZ-TJ8kPBV-c6jn59vb669W2ufn47v3V5U0TlGa2UTyyFAMkEWWMUQsTb3nnvZc-diCjBsF9QOYxGYlc887EaJVXkLSJUopz8uaYu8_z3QHL4sa-BBwGP-F8KM5wY03XqQpeHMGQ51LqR90-96PPqwPmHgw6Bm7745MD67irBuvGq1P04XbE-J8_Kqvz16e5L8EPKfup-vqHKa6YMKxi8ojdz0M1XH4Ph3vMbod-WHaO1SO57hqwljNeX81Dy4q_RLyJhw</recordid><startdate>199202</startdate><enddate>199202</enddate><creator>Cléroux, Jean</creator><creator>Kouamé, NʼGuessan</creator><creator>Nadeau, André</creator><creator>Coulombe, Denis</creator><creator>Lacourcière, Yves</creator><general>American Heart Association, Inc</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199202</creationdate><title>Aftereffects of Exercise on Regional and Systemic Hemodynamics in Hypertension</title><author>Cléroux, Jean ; Kouamé, NʼGuessan ; Nadeau, André ; Coulombe, Denis ; Lacourcière, Yves</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5609-52d0fdc1f3d4ddd637db28aaa4ad814d6132ace0aef74e26287dd95a51f67d443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adult</topic><topic>Arterial hypertension. Arterial hypotension</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Cardiology. Vascular system</topic><topic>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</topic><topic>Exercise</topic><topic>Female</topic><topic>Forearm - blood supply</topic><topic>Heart Rate</topic><topic>Hemodynamics</topic><topic>Humans</topic><topic>Hypertension - blood</topic><topic>Hypertension - physiopathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Norepinephrine - blood</topic><topic>Random Allocation</topic><topic>Reference Values</topic><topic>Regional Blood Flow</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cléroux, Jean</creatorcontrib><creatorcontrib>Kouamé, NʼGuessan</creatorcontrib><creatorcontrib>Nadeau, André</creatorcontrib><creatorcontrib>Coulombe, Denis</creatorcontrib><creatorcontrib>Lacourcière, Yves</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Hypertension (Dallas, Tex. 1979)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cléroux, Jean</au><au>Kouamé, NʼGuessan</au><au>Nadeau, André</au><au>Coulombe, Denis</au><au>Lacourcière, Yves</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aftereffects of Exercise on Regional and Systemic Hemodynamics in Hypertension</atitle><jtitle>Hypertension (Dallas, Tex. 1979)</jtitle><addtitle>Hypertension</addtitle><date>1992-02</date><risdate>1992</risdate><volume>19</volume><issue>2</issue><spage>183</spage><epage>191</epage><pages>183-191</pages><issn>0194-911X</issn><eissn>1524-4563</eissn><coden>HPRTDN</coden><abstract>Several studies have indicated that a single bout of physical exercise induced a significant antihypertensive effect during the hours after the activity. However, little information is presently available on the underlying hemodynamic changes. We examined 13 essential hypertensive patients and nine nonnotensive subjects in a randomized, crossover study design during 3 hours after a 30-minute period of upright leg cycling at 50% of peak aerobic capacity and during 3 hours after a 30-minute control period of rest Blood pressure, heart rate, cardiac output, total peripheral resistance, and regional vascular resistance in the forearm as well as venous plasma catecholamine concentrations were measured repeatedly. After exercise, systolic (−11±2 mm Hg) and diastolic (−4±1 mm Hg) blood pressures, total peripheral resistance (−27±5%), forearm vascular resistance (−25±6%), and plasma norepinephrine levels (−21±7%) were significantly (p<0.05) decreased, and cardiac output was increased (+31±8%) compared with control in hypertensive subjects. In contrast, in normotensive subjects blood pressure, forearm vascular resistance, and plasma norepinephrine were unchanged, and systemic hemodynamics changed to a lesser extent than in hypertensive subjects after exercise. It is concluded that a decrease in regional vascular resistance in skeletal muscles and possibly in the skin in hypertensive patients may contribute importantly to the antihypertensive effect of prior exercise. A decreased sympathetic nervous activity, as seen from lower plasma norepinephrine levels, may be involved in this effect.</abstract><cop>Philadelphia, PA</cop><cop>Hagerstown, MD</cop><pub>American Heart Association, Inc</pub><pmid>1737653</pmid><doi>10.1161/01.hyp.19.2.183</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0194-911X |
| ispartof | Hypertension (Dallas, Tex. 1979), 1992-02, Vol.19 (2), p.183-191 |
| issn | 0194-911X 1524-4563 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_72797885 |
| source | MEDLINE; American Heart Association Journals; Journals@Ovid Complete; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Clinical manifestations. Epidemiology. Investigative techniques. Etiology Exercise Female Forearm - blood supply Heart Rate Hemodynamics Humans Hypertension - blood Hypertension - physiopathology Male Medical sciences Norepinephrine - blood Random Allocation Reference Values Regional Blood Flow |
| title | Aftereffects of Exercise on Regional and Systemic Hemodynamics in Hypertension |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T10%3A59%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Aftereffects%20of%20Exercise%20on%20Regional%20and%20Systemic%20Hemodynamics%20in%20Hypertension&rft.jtitle=Hypertension%20(Dallas,%20Tex.%201979)&rft.au=Cl%C3%A9roux,%20Jean&rft.date=1992-02&rft.volume=19&rft.issue=2&rft.spage=183&rft.epage=191&rft.pages=183-191&rft.issn=0194-911X&rft.eissn=1524-4563&rft.coden=HPRTDN&rft_id=info:doi/10.1161/01.hyp.19.2.183&rft_dat=%3Cproquest_cross%3E72797885%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=72797885&rft_id=info:pmid/1737653&rfr_iscdi=true |