Translation of hSNM1 is mediated by an internal ribosome entry site that upregulates expression during mitosis

SNM1 is involved in the repair of DNA interstrand cross-links (ICLs) in Saccharomyces cerevisiae and possibly in human cells, although relatively little is known about its biochemical function. The hSNM1 contains a long 5′ untranslated region (5′UTR) predicted to fold into a complex secondary struct...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	DNA repair 2002-05, Vol.1 (5), p.379-390
Hauptverfasser:	Zhang, Xiaoshan, Richie, Christopher, Legerski, Randy J.
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions - chemistry 5' Untranslated Regions - physiology Biological and medical sciences Cell Division Cells, Cultured Chemical mutagenesis Cross-linking DNA Damage DNA Primers - chemistry DNA Repair DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Endodeoxyribonucleases Flow Cytometry Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology Green Fluorescent Proteins Humans Internal ribosome entry site (IRES) Luminescent Proteins - metabolism Medical sciences Mitosis Mitosis - physiology Molecular and cellular biology Molecular genetics Mutagenesis. Repair Nuclear Proteins - genetics Nuclear Proteins - metabolism Nucleic Acid Conformation Open Reading Frames Open reading frames (ORFs) Polymerase Chain Reaction Protein Biosynthesis Ribosomes - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Toxicology Transfection Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!