Suppression of bilirubin production in the crigler-najjar type I syndrome : studies with the heme oxygenase inhibitor tin-mesoporphyrin

The heme oxygenase inhibitor tin-mesoporphyrin was used to moderate hyperbilirubinemia in two 17-year-old boys with Crigler-Najjar type I syndrome. Both patients had histories of recent, progressive neurological deterioration and plasma bilirubin concentrations on admission to the hospital were 34.5...

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Veröffentlicht in:	Pediatrics (Evanston) 1992-02, Vol.89 (2), p.175-182
Hauptverfasser:	GALBRAITH, R. A, DRUMMOND, G. S, KAPPAS, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Bilirubin Bilirubin - metabolism Biological and medical sciences Care and treatment Combined Modality Therapy Crigler-Najjar Syndrome - drug therapy Crigler-Najjar Syndrome - therapy Diet Therapy Digestive system Drug Evaluation Health aspects Heme Oxygenase (Decyclizing) - antagonists & inhibitors Humans Hyperbilirubinemia Male Measurement Medical sciences Metalloporphyrins - therapeutic use Pharmacology. Drug treatments Phototherapy Plasmapheresis Porphyrins Time Factors
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