Human astrocytes express membrane cofactor protein (CD46), a regulator of complement activation

Expression of membrane cofactor protein (CD46) on cultured human astrocytes was demonstrated by indirect immunofluorescence microscopy and flow cytometry following staining with a monoclonal antibody specific for CD46. Western transfer and immunoblotting detected a doublet of M r 66,000 and 56,000....

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Veröffentlicht in:	Journal of neuroimmunology 1992-02, Vol.36 (2), p.199-208
Hauptverfasser:	Gordon, David L., Sadlon, Tania A., Wesselingh, Steve L., Russell, Sarah M., Johnstone, Ricky W., Purcell, Damian F.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - analysis Antigens, CD - genetics Astrocyte Astrocytes - immunology Base Sequence Biological and medical sciences CD55 Antigens Cells, Cultured Complement Complement Activation Cytomegalovirus Infections - immunology Female Fundamental and applied biological sciences. Psychology Fundamental immunology Histocompatibility Antigens Class I - analysis Histocompatibility Antigens Class II - analysis Humans Immunobiology Immunoblotting Membrane Cofactor Protein Membrane Glycoproteins - analysis Membrane Glycoproteins - genetics Molecular Sequence Data Pregnancy Regulator of complement activation RNA, Messenger - analysis Up-Regulation
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