Differential induction of the c-fos promoter through distinct PDGF receptor-mediated signaling pathways

The multiple isoforms of PDGF induce fibroblastic mitogenesis through two distinct PDGF receptors, α and β. The molecular mechanisms by which these α and β PDGF receptors regulate gene expression are poorly understood. We present data which indicates that differential induction of c‐fos gene express...

Ausführliche Beschreibung