Comparison of cefotaxime with ceftriaxone given intramuscularly 12-hourly for community-acquired pneumonia

Cefotaxime 1 g intramuscularly (i.m.) 12-hourly was compared with ceftriaxone 1 g i.m. 12-hourly in adult patients requiring hospitalization with uncomplicated community-acquired pneumonia. Fifty-two patients were enrolled and two were subsequently withdrawn, leaving 50 patients who completed the st...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Diagnostic microbiology and infectious disease 1992, Vol.15 (1), p.81-84
Hauptverfasser: Dansey, Roger D., Jacka, Peter J., Strachan, Simon A., Hay, Malcolm
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 84
container_issue 1
container_start_page 81
container_title Diagnostic microbiology and infectious disease
container_volume 15
creator Dansey, Roger D.
Jacka, Peter J.
Strachan, Simon A.
Hay, Malcolm
description Cefotaxime 1 g intramuscularly (i.m.) 12-hourly was compared with ceftriaxone 1 g i.m. 12-hourly in adult patients requiring hospitalization with uncomplicated community-acquired pneumonia. Fifty-two patients were enrolled and two were subsequently withdrawn, leaving 50 patients who completed the study; 23 received cefotaxime and 27 received ceftriaxone. Clinical cure was achieved in 49 of the 50 patients (98%). One treatment failure occurred in a patient who received ceftriaxone. The only significant pathogen isolated from the pretreatment sputum cultures was Streptococcus pneumoniae (50%). All isolates were sensitive to both drugs. Cefotaxime 1 g i.m. 12-hourly was as effective as ceftriaxone in the treatment of patients with uncomplicated community-acquired pneumonia requiring hospital admission.
doi_str_mv 10.1016/0732-8893(92)90060-7
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72787674</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0732889392900607</els_id><sourcerecordid>72787674</sourcerecordid><originalsourceid>FETCH-LOGICAL-c386t-fccf15de1d4153c1cd78d8289dd79175b10245b04b3b57caea5a85c790e5c1e93</originalsourceid><addsrcrecordid>eNp9kE1v1DAQhi0EKtvCPwApB4TKIWDH8dq-VEIrvqRKXOBsOeMJdRXbWzsu3X9Pwq7KjdPM6H1mNHoIecXoe0bZ9gOVvGuV0vxSd-80pVvayidkw5TULaWSPiWbR-Q5OS_lllLW6Z6ekTMmOWVKbcjtLoW9zb6k2KSxARzTbB98wOa3n2_Wec7ePqSIzS9_j7Hxcc421AJ1snk6NKxrb1JduzHlBlIINfr50Fq4qz6ja_YRa0jR2xfk2Wingi9P9YL8_Pzpx-5re_39y7fdx-sWuNrO7QgwMuGQuZ4JDgycVE51SjsnNZNiYLTrxUD7gQ9CgkUrrBIgNUUBDDW_IG-Pd_c53VUsswm-AE6TjZhqMbKTSm5lv4D9EYScSsk4mn32weaDYdSsis3qz6z-jO7MX8VGLmuvT_frEND9Wzo6XfI3p9wWsNOYbQRfHjHBuO4FX7CrI4aLi3uP2RTwGAHdog1m45L__x9_AEfBmhU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72787674</pqid></control><display><type>article</type><title>Comparison of cefotaxime with ceftriaxone given intramuscularly 12-hourly for community-acquired pneumonia</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Dansey, Roger D. ; Jacka, Peter J. ; Strachan, Simon A. ; Hay, Malcolm</creator><creatorcontrib>Dansey, Roger D. ; Jacka, Peter J. ; Strachan, Simon A. ; Hay, Malcolm</creatorcontrib><description>Cefotaxime 1 g intramuscularly (i.m.) 12-hourly was compared with ceftriaxone 1 g i.m. 12-hourly in adult patients requiring hospitalization with uncomplicated community-acquired pneumonia. Fifty-two patients were enrolled and two were subsequently withdrawn, leaving 50 patients who completed the study; 23 received cefotaxime and 27 received ceftriaxone. Clinical cure was achieved in 49 of the 50 patients (98%). One treatment failure occurred in a patient who received ceftriaxone. The only significant pathogen isolated from the pretreatment sputum cultures was Streptococcus pneumoniae (50%). All isolates were sensitive to both drugs. Cefotaxime 1 g i.m. 12-hourly was as effective as ceftriaxone in the treatment of patients with uncomplicated community-acquired pneumonia requiring hospital admission.</description><identifier>ISSN: 0732-8893</identifier><identifier>EISSN: 1879-0070</identifier><identifier>DOI: 10.1016/0732-8893(92)90060-7</identifier><identifier>PMID: 1730188</identifier><identifier>CODEN: DMIDDZ</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Antibacterial agents ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Biological and medical sciences ; Cefotaxime - administration &amp; dosage ; Cefotaxime - therapeutic use ; Ceftriaxone - administration &amp; dosage ; Ceftriaxone - therapeutic use ; Drug Administration Schedule ; Humans ; Injections, Intramuscular ; Male ; Medical sciences ; Middle Aged ; Pharmacology. Drug treatments ; Pneumonia - drug therapy</subject><ispartof>Diagnostic microbiology and infectious disease, 1992, Vol.15 (1), p.81-84</ispartof><rights>1992</rights><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-fccf15de1d4153c1cd78d8289dd79175b10245b04b3b57caea5a85c790e5c1e93</citedby><cites>FETCH-LOGICAL-c386t-fccf15de1d4153c1cd78d8289dd79175b10245b04b3b57caea5a85c790e5c1e93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0732-8893(92)90060-7$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>309,310,314,780,784,789,790,3550,4024,4050,4051,23930,23931,25140,27923,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=5139453$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1730188$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dansey, Roger D.</creatorcontrib><creatorcontrib>Jacka, Peter J.</creatorcontrib><creatorcontrib>Strachan, Simon A.</creatorcontrib><creatorcontrib>Hay, Malcolm</creatorcontrib><title>Comparison of cefotaxime with ceftriaxone given intramuscularly 12-hourly for community-acquired pneumonia</title><title>Diagnostic microbiology and infectious disease</title><addtitle>Diagn Microbiol Infect Dis</addtitle><description>Cefotaxime 1 g intramuscularly (i.m.) 12-hourly was compared with ceftriaxone 1 g i.m. 12-hourly in adult patients requiring hospitalization with uncomplicated community-acquired pneumonia. Fifty-two patients were enrolled and two were subsequently withdrawn, leaving 50 patients who completed the study; 23 received cefotaxime and 27 received ceftriaxone. Clinical cure was achieved in 49 of the 50 patients (98%). One treatment failure occurred in a patient who received ceftriaxone. The only significant pathogen isolated from the pretreatment sputum cultures was Streptococcus pneumoniae (50%). All isolates were sensitive to both drugs. Cefotaxime 1 g i.m. 12-hourly was as effective as ceftriaxone in the treatment of patients with uncomplicated community-acquired pneumonia requiring hospital admission.</description><subject>Adult</subject><subject>Antibacterial agents</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Biological and medical sciences</subject><subject>Cefotaxime - administration &amp; dosage</subject><subject>Cefotaxime - therapeutic use</subject><subject>Ceftriaxone - administration &amp; dosage</subject><subject>Ceftriaxone - therapeutic use</subject><subject>Drug Administration Schedule</subject><subject>Humans</subject><subject>Injections, Intramuscular</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pharmacology. Drug treatments</subject><subject>Pneumonia - drug therapy</subject><issn>0732-8893</issn><issn>1879-0070</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1v1DAQhi0EKtvCPwApB4TKIWDH8dq-VEIrvqRKXOBsOeMJdRXbWzsu3X9Pwq7KjdPM6H1mNHoIecXoe0bZ9gOVvGuV0vxSd-80pVvayidkw5TULaWSPiWbR-Q5OS_lllLW6Z6ekTMmOWVKbcjtLoW9zb6k2KSxARzTbB98wOa3n2_Wec7ePqSIzS9_j7Hxcc421AJ1snk6NKxrb1JduzHlBlIINfr50Fq4qz6ja_YRa0jR2xfk2Wingi9P9YL8_Pzpx-5re_39y7fdx-sWuNrO7QgwMuGQuZ4JDgycVE51SjsnNZNiYLTrxUD7gQ9CgkUrrBIgNUUBDDW_IG-Pd_c53VUsswm-AE6TjZhqMbKTSm5lv4D9EYScSsk4mn32weaDYdSsis3qz6z-jO7MX8VGLmuvT_frEND9Wzo6XfI3p9wWsNOYbQRfHjHBuO4FX7CrI4aLi3uP2RTwGAHdog1m45L__x9_AEfBmhU</recordid><startdate>1992</startdate><enddate>1992</enddate><creator>Dansey, Roger D.</creator><creator>Jacka, Peter J.</creator><creator>Strachan, Simon A.</creator><creator>Hay, Malcolm</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1992</creationdate><title>Comparison of cefotaxime with ceftriaxone given intramuscularly 12-hourly for community-acquired pneumonia</title><author>Dansey, Roger D. ; Jacka, Peter J. ; Strachan, Simon A. ; Hay, Malcolm</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-fccf15de1d4153c1cd78d8289dd79175b10245b04b3b57caea5a85c790e5c1e93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adult</topic><topic>Antibacterial agents</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Biological and medical sciences</topic><topic>Cefotaxime - administration &amp; dosage</topic><topic>Cefotaxime - therapeutic use</topic><topic>Ceftriaxone - administration &amp; dosage</topic><topic>Ceftriaxone - therapeutic use</topic><topic>Drug Administration Schedule</topic><topic>Humans</topic><topic>Injections, Intramuscular</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pharmacology. Drug treatments</topic><topic>Pneumonia - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dansey, Roger D.</creatorcontrib><creatorcontrib>Jacka, Peter J.</creatorcontrib><creatorcontrib>Strachan, Simon A.</creatorcontrib><creatorcontrib>Hay, Malcolm</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Diagnostic microbiology and infectious disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dansey, Roger D.</au><au>Jacka, Peter J.</au><au>Strachan, Simon A.</au><au>Hay, Malcolm</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of cefotaxime with ceftriaxone given intramuscularly 12-hourly for community-acquired pneumonia</atitle><jtitle>Diagnostic microbiology and infectious disease</jtitle><addtitle>Diagn Microbiol Infect Dis</addtitle><date>1992</date><risdate>1992</risdate><volume>15</volume><issue>1</issue><spage>81</spage><epage>84</epage><pages>81-84</pages><issn>0732-8893</issn><eissn>1879-0070</eissn><coden>DMIDDZ</coden><abstract>Cefotaxime 1 g intramuscularly (i.m.) 12-hourly was compared with ceftriaxone 1 g i.m. 12-hourly in adult patients requiring hospitalization with uncomplicated community-acquired pneumonia. Fifty-two patients were enrolled and two were subsequently withdrawn, leaving 50 patients who completed the study; 23 received cefotaxime and 27 received ceftriaxone. Clinical cure was achieved in 49 of the 50 patients (98%). One treatment failure occurred in a patient who received ceftriaxone. The only significant pathogen isolated from the pretreatment sputum cultures was Streptococcus pneumoniae (50%). All isolates were sensitive to both drugs. Cefotaxime 1 g i.m. 12-hourly was as effective as ceftriaxone in the treatment of patients with uncomplicated community-acquired pneumonia requiring hospital admission.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>1730188</pmid><doi>10.1016/0732-8893(92)90060-7</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0732-8893
ispartof Diagnostic microbiology and infectious disease, 1992, Vol.15 (1), p.81-84
issn 0732-8893
1879-0070
language eng
recordid cdi_proquest_miscellaneous_72787674
source MEDLINE; Elsevier ScienceDirect Journals Complete
subjects Adult
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Cefotaxime - administration & dosage
Cefotaxime - therapeutic use
Ceftriaxone - administration & dosage
Ceftriaxone - therapeutic use
Drug Administration Schedule
Humans
Injections, Intramuscular
Male
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Pneumonia - drug therapy
title Comparison of cefotaxime with ceftriaxone given intramuscularly 12-hourly for community-acquired pneumonia
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T00%3A12%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparison%20of%20cefotaxime%20with%20ceftriaxone%20given%20intramuscularly%2012-hourly%20for%20community-acquired%20pneumonia&rft.jtitle=Diagnostic%20microbiology%20and%20infectious%20disease&rft.au=Dansey,%20Roger%20D.&rft.date=1992&rft.volume=15&rft.issue=1&rft.spage=81&rft.epage=84&rft.pages=81-84&rft.issn=0732-8893&rft.eissn=1879-0070&rft.coden=DMIDDZ&rft_id=info:doi/10.1016/0732-8893(92)90060-7&rft_dat=%3Cproquest_cross%3E72787674%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=72787674&rft_id=info:pmid/1730188&rft_els_id=0732889392900607&rfr_iscdi=true