In Vitro Inhibition of [3H]-Angiotensin II Binding on the Human AT1 Receptor by Proanthocyanidins from Guazuma ulmifolia Bark

Abstract A bioassay-guided fractionation of the 70 % acetone extract of the bark of GUAZUMA ULMIFOLIA Lam. on the inhibition of angiotensin II binding to the AT 1 receptor led to the isolation and identification of bioactive oligomeric and polymeric proanthocyanidins consisting mainly of (-)-epicate...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Planta medica 2002-12, Vol.68 (12), p.1066-1071
Hauptverfasser:	Caballero-George, Catherina, Vanderheyden, Patrick M., De Bruyne, Tess, Shahat, Abdel-Atty, Van den Heuvel, Hilde, Solis, Pablo N., Gupta, Mahabir P., Claeys, Magda, Pieters, Luc, Vauquelin, Georges, Vlietinck, Arnold J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - metabolism Anthocyanins - pharmacology Binding Sites - drug effects Binding, Competitive - drug effects Dose-Response Relationship, Drug Humans Malvaceae Original Paper Plant Bark - chemistry Plant Extracts - pharmacology Proanthocyanidins Receptor, Angiotensin, Type 1 Receptors, Angiotensin - drug effects Receptors, Angiotensin - metabolism Tritium
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!