Rheological Analysis of the Adhesive Interactions of Red Blood Cells Parasitized by Plasmodium falciparum

Adhesion of parasitized red blood cells (RBCs) to vascular endothelium is thought to be a key factor in the pathology of falciparum malaria. However, quantitative analyses of the intercellular forces and of the effects of flow on adhesion have been lacking. We have characterized cytoadhesion of RBCs...

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Veröffentlicht in:	Blood 1992-02, Vol.79 (3), p.798-807
Hauptverfasser:	Nash, G.B., Cooke, B.M., Marsh, K., Berendt, A., Newbold, C., Stuart, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Adhesion Endothelium, Vascular - cytology Erythrocytes - cytology Erythrocytes - parasitology Glutaral - chemistry Human protozoal diseases Humans In Vitro Techniques Infectious diseases Malaria Malaria, Falciparum - blood Medical sciences Parasitic diseases Plasmodium falciparum - growth & development Plasmodium falciparum - pathogenicity Protozoal diseases Rheology Temperature
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