Identification of a 1,25-Dihydroxyvitamin D3-Response Element in the 5' Flanking Region of the Rat Calbindin D-9k Gene

The rat calbindin D-9k gene is transcriptionally regulated by 1,25-dihydroxyvitamin D3in the intestine. We have examined the 5'-flanking region of this gene and identified a 1,25-dihydroxyvitamin D3-responsive element (DRE) between nucleotides -489 and -445. This element confers 1,25-dihydroxyv...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1992-01, Vol.89 (2), p.603-607
Hauptverfasser:	Darwish, Hisham M., Deluca, Hector F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Base Sequence Binding Sites Biological and medical sciences Calbindins Calcitriol - physiology DNA DNA Mutational Analysis DNA probes DNA-Binding Proteins - physiology Exons Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation Genes Genetic vectors Molecular and cellular biology Molecular genetics Molecular Sequence Data Nucleotides Promoter regions Rats Receptors Receptors, Calcitriol Receptors, Steroid - physiology Regulatory Sequences, Nucleic Acid S100 Calcium Binding Protein G - genetics Transcription, Genetic Vitamin D
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