Etiopathogenesis of acute hepatic failure: Eastern versus Western countries
Etiopathogenesis of acute hepatic failure (AHF) in Eastern and Western countries is distinct. In the East hepatitis viruses cause AHF in more than 95% of such cases, while causes of AHF in the West are quite heterogenous. Hepatitis E virus is the major etiological agent of AHF in countries like Indi...
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| Veröffentlicht in: | Journal of gastroenterology and hepatology 2002-12, Vol.17 (s3), p.S268-S273 |
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| container_issue | s3 |
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| container_title | Journal of gastroenterology and hepatology |
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| creator | ACHARYA, SK BATRA, Y HAZARI, S CHOUDHURY, V PANDA, SK DATTAGUPTA, S |
| description | Etiopathogenesis of acute hepatic failure (AHF) in Eastern and Western countries is distinct. In the East hepatitis viruses cause AHF in more than 95% of such cases, while causes of AHF in the West are quite heterogenous. Hepatitis E virus is the major etiological agent of AHF in countries like India where the virus is hyperendemic. Occult HBV infection may also be causing AHF in a sizable proportion of cases in areas where chronic HBV infection frequency is high. Paracetamol causes AHF in about 70% cases in the UK and about 20% cases in USA, whereas in France and Denmark, non‐steroidal anti‐inflammatory drugs are more frequently associated with AHF. Hepatitis B virus causes AHF in about one‐third of cases in the latter two countries.
© 2002 Blackwell Publishing Asia Pty Ltd |
| doi_str_mv | 10.1046/j.1440-1746.17.s3.12.x |
| format | Article |
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| ispartof | Journal of gastroenterology and hepatology, 2002-12, Vol.17 (s3), p.S268-S273 |
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| language | eng |
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| source | Wiley Online Library Journals【Remote access available】; MEDLINE |
| subjects | Europe Humans India Liver Failure, Acute - etiology Liver Failure, Acute - pathology United States |
| title | Etiopathogenesis of acute hepatic failure: Eastern versus Western countries |
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