Cutting Edge: Virus-Specific CD4+ Memory T Cells in Nonlymphoid Tissues Express a Highly Activated Phenotype

Recent studies have shown that CD4(+) memory T cells persist in nonlymphoid organs following infections. However, the development and phenotype of these peripheral memory cells are poorly defined. In this study, multimerized MHC-Ig fusion proteins, with a covalently attached peptide sequence from th...

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Veröffentlicht in:	The Journal of immunology (1950) 2002-12, Vol.169 (12), p.6655-6658
Hauptverfasser:	Cauley, Linda S, Cookenham, Tres, Miller, Timothy B, Adams, Pamela S, Vignali, Kate M, Vignali, Dario A. A, Woodland, David L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD4-Positive T-Lymphocytes - chemistry CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism CD4-Positive T-Lymphocytes - virology Epitopes, T-Lymphocyte - immunology Female Histocompatibility Antigens Class II - analysis Histocompatibility Antigens Class II - genetics HN Protein - immunology Immunoglobulin Fc Fragments - analysis Immunoglobulin Fc Fragments - genetics Immunologic Memory Immunophenotyping Lung - immunology Lung - metabolism Lung - pathology Lung - virology Lymphocyte Activation Lymphocyte Count Lymphoid Tissue - immunology Lymphoid Tissue - pathology Lymphoid Tissue - virology Mice Mice, Inbred C57BL Recombinant Fusion Proteins - analysis Recombinant Fusion Proteins - biosynthesis Respirovirus Infections - immunology Respirovirus Infections - pathology Respirovirus Infections - virology Sendai virus - immunology T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism T-Lymphocyte Subsets - virology
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