Plasma levels and cardiovascular gene expression of urotensin-II in human heart failure

The peptide urotensin-II (U-II) has been described as most potent vasoconstrictor identified so far, but plasma values in humans and its role in cardiovascular pathophysiology are unknown. We investigated circulating urotensin-II and its potential role in human congestive heart failure (CHF). We enr...

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Veröffentlicht in:	Regulatory peptides 2002-12, Vol.110 (1), p.33-38
Hauptverfasser:	Dschietzig, Thomas, Bartsch, Cornelia, Pregla, Rainer, Zurbrügg, Heinz Robert, Armbruster, Franz Paul, Richter, Christoph, Laule, Michael, Romeyke, Elfrun, Neubert, Charlotte, Voelter, Wolfgang, Baumann, Gert, Stangl, Karl
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cardiology. Vascular system Female Gene Expression Heart Heart Failure - blood Heart Failure - genetics Heart Failure - physiopathology Heart failure, cardiogenic pulmonary edema, cardiac enlargement Hemodynamics Humans Immunoassay Immunoenzyme Techniques Male Medical sciences Middle Aged Myocardium - metabolism Peptides Protein Precursors - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis RNA, Messenger - biosynthesis Urotensins - biosynthesis Urotensins - blood Urotensins - genetics Vasodilator Agents - therapeutic use
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