The decomposition of thionitrites

The mechanism of thionitrite decomposition, both in vivo and in vitro, remains unclear. Thionitrite stability is highly variable; it is a complex function of thionitrite structure and environmental condition. Several recent advances clarify the role of unimolecular homlytic decomposition, metal-cata...

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Veröffentlicht in:	Current Opinion in Chemical Biology 2002-12, Vol.6 (6), p.779-785
Hauptverfasser:	Stamler, Jonathan S, Toone, Eric J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehyde Oxidoreductases - metabolism Animals Copper - chemistry Copper - pharmacology Drug Stability Humans Kinetics Nitric oxide Nitric Oxide - chemistry Nitrites - chemistry Nitrites - metabolism nitrosothiol stability Oxidation-Reduction Oxygen - chemistry Oxygen - pharmacology Sulfhydryl Compounds - chemistry Sulfhydryl Compounds - metabolism Sulfur - chemistry thionitrite stability
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