Oral dexketoprofen for pain treatment during diagnostic hysteroscopy in postmenopausal women
Objective: To assess the efficacy of dexketoprofen (DEX) in reducing pain at different stages of the hysteroscopic procedure in comparison with local anaesthesia in menopausal women. Methods: Menopausal patients affected by uterine bleeding submitted to diagnostic hysteroscopy, were randomised to re...
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| Veröffentlicht in: | Maturitas 2002-12, Vol.43 (4), p.277-281 |
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| creator | Mercorio, Francesco De Simone, Raffaella Landi, Paola Sarchianaki, Anna Tessitore, Giovanni Nappi, Carmine |
| description | Objective: To assess the efficacy of dexketoprofen (DEX) in reducing pain at different stages of the hysteroscopic procedure in comparison with local anaesthesia in menopausal women.
Methods: Menopausal patients affected by uterine bleeding submitted to diagnostic hysteroscopy, were randomised to receive either 25 mg DEX tablet (
n=148) or intracervical injection of 5 ml mepivacaine 2% (
n=150). Pain suffered during the procedure itself and 30, 60, 120 min after, was scored on the 11 point Visual Analogic Scale, recorded and analysed.
Results: No statistical difference were noted during the procedure itself in both groups of treatment. Patients treated with DEX has significantly less postoperative pain.
Conclusions: DEX is not superior to mepivacaine in reducing the discomfort of the procedure but does significantly reduce postoperative pain. |
| doi_str_mv | 10.1016/S0378-5122(02)00186-X |
| format | Article |
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Methods: Menopausal patients affected by uterine bleeding submitted to diagnostic hysteroscopy, were randomised to receive either 25 mg DEX tablet (
n=148) or intracervical injection of 5 ml mepivacaine 2% (
n=150). Pain suffered during the procedure itself and 30, 60, 120 min after, was scored on the 11 point Visual Analogic Scale, recorded and analysed.
Results: No statistical difference were noted during the procedure itself in both groups of treatment. Patients treated with DEX has significantly less postoperative pain.
Conclusions: DEX is not superior to mepivacaine in reducing the discomfort of the procedure but does significantly reduce postoperative pain.</description><identifier>ISSN: 0378-5122</identifier><identifier>EISSN: 1873-4111</identifier><identifier>DOI: 10.1016/S0378-5122(02)00186-X</identifier><identifier>PMID: 12468136</identifier><identifier>CODEN: MATUDK</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject><![CDATA[Administration, Oral ; Analgesics ; Anti-Inflammatory Agents, Non-Steroidal - administration & dosage ; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use ; Biological and medical sciences ; Dexketoprofen ; Female ; Humans ; Hysteroscopy ; Injections ; Ketoprofen - administration & dosage ; Ketoprofen - analogs & derivatives ; Ketoprofen - therapeutic use ; Medical sciences ; Mepivacaine - administration & dosage ; Mepivacaine - therapeutic use ; Neuropharmacology ; Pain ; Pain Measurement ; Pain, Postoperative - drug therapy ; Pharmacology. Drug treatments ; Postmenopause ; Treatment Outcome ; Tromethamine - administration & dosage ; Tromethamine - analogs & derivatives ; Tromethamine - therapeutic use]]></subject><ispartof>Maturitas, 2002-12, Vol.43 (4), p.277-281</ispartof><rights>2002 Elsevier Science Ireland Ltd</rights><rights>2003 INIST-CNRS</rights><rights>Copyright 2002 Elsevier Science Ireland Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c391t-266ffde16819e1a4744ce39e91042005a8bae03e822e0b3537dc9ef58e80ad083</citedby><cites>FETCH-LOGICAL-c391t-266ffde16819e1a4744ce39e91042005a8bae03e822e0b3537dc9ef58e80ad083</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0378-5122(02)00186-X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14355844$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12468136$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mercorio, Francesco</creatorcontrib><creatorcontrib>De Simone, Raffaella</creatorcontrib><creatorcontrib>Landi, Paola</creatorcontrib><creatorcontrib>Sarchianaki, Anna</creatorcontrib><creatorcontrib>Tessitore, Giovanni</creatorcontrib><creatorcontrib>Nappi, Carmine</creatorcontrib><title>Oral dexketoprofen for pain treatment during diagnostic hysteroscopy in postmenopausal women</title><title>Maturitas</title><addtitle>Maturitas</addtitle><description>Objective: To assess the efficacy of dexketoprofen (DEX) in reducing pain at different stages of the hysteroscopic procedure in comparison with local anaesthesia in menopausal women.
Methods: Menopausal patients affected by uterine bleeding submitted to diagnostic hysteroscopy, were randomised to receive either 25 mg DEX tablet (
n=148) or intracervical injection of 5 ml mepivacaine 2% (
n=150). Pain suffered during the procedure itself and 30, 60, 120 min after, was scored on the 11 point Visual Analogic Scale, recorded and analysed.
Results: No statistical difference were noted during the procedure itself in both groups of treatment. Patients treated with DEX has significantly less postoperative pain.
Conclusions: DEX is not superior to mepivacaine in reducing the discomfort of the procedure but does significantly reduce postoperative pain.</description><subject>Administration, Oral</subject><subject>Analgesics</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - administration & dosage</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Dexketoprofen</subject><subject>Female</subject><subject>Humans</subject><subject>Hysteroscopy</subject><subject>Injections</subject><subject>Ketoprofen - administration & dosage</subject><subject>Ketoprofen - analogs & derivatives</subject><subject>Ketoprofen - therapeutic use</subject><subject>Medical sciences</subject><subject>Mepivacaine - administration & dosage</subject><subject>Mepivacaine - therapeutic use</subject><subject>Neuropharmacology</subject><subject>Pain</subject><subject>Pain Measurement</subject><subject>Pain, Postoperative - drug therapy</subject><subject>Pharmacology. Drug treatments</subject><subject>Postmenopause</subject><subject>Treatment Outcome</subject><subject>Tromethamine - administration & dosage</subject><subject>Tromethamine - analogs & derivatives</subject><subject>Tromethamine - therapeutic use</subject><issn>0378-5122</issn><issn>1873-4111</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1LHDEUhoNU6lb7Eyxz02Ivxp58zWSuShFbC4IXVvCiELLJGZt2djImmdb992a7i14KgUPCc07e8xByTOGUAm0-XQNvVS0pYyfAPgJQ1dS3e2RBVctrQSl9RRZPyAF5k9JvAJDAxWtyQJloFOXNgvy8imaoHD78wRymGHocqz7EajJ-rHJEk1c45srN0Y93lfPmbgwpe1v9WqeMMSQbpnVV2Kk8FzRMZk5l4r9QLkdkvzdDwre7ekhuvp7_OLuoL6--fT_7cllb3tFcs6bpe4e0ROqQGtEKYZF32FEQrGQ2amkQOCrGEJZc8tbZDnupUIFxoPgh-bCdWxa4nzFlvfLJ4jCYEcOcdMtaSbtOFlBuQVuSp4i9nqJfmbjWFPRGq_6vVW-caShno1Xflr53uw_m5Qrdc9fOYwHe7wCTrBn6aEbr0zMnuJRKiMJ93nJYdPz1GHWyHkeLzke0WbvgX4jyCJSBljE</recordid><startdate>20021210</startdate><enddate>20021210</enddate><creator>Mercorio, Francesco</creator><creator>De Simone, Raffaella</creator><creator>Landi, Paola</creator><creator>Sarchianaki, Anna</creator><creator>Tessitore, Giovanni</creator><creator>Nappi, Carmine</creator><general>Elsevier Ireland Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20021210</creationdate><title>Oral dexketoprofen for pain treatment during diagnostic hysteroscopy in postmenopausal women</title><author>Mercorio, Francesco ; De Simone, Raffaella ; Landi, Paola ; Sarchianaki, Anna ; Tessitore, Giovanni ; Nappi, Carmine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-266ffde16819e1a4744ce39e91042005a8bae03e822e0b3537dc9ef58e80ad083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Administration, Oral</topic><topic>Analgesics</topic><topic>Anti-Inflammatory Agents, Non-Steroidal - administration & dosage</topic><topic>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Dexketoprofen</topic><topic>Female</topic><topic>Humans</topic><topic>Hysteroscopy</topic><topic>Injections</topic><topic>Ketoprofen - administration & dosage</topic><topic>Ketoprofen - analogs & derivatives</topic><topic>Ketoprofen - therapeutic use</topic><topic>Medical sciences</topic><topic>Mepivacaine - administration & dosage</topic><topic>Mepivacaine - therapeutic use</topic><topic>Neuropharmacology</topic><topic>Pain</topic><topic>Pain Measurement</topic><topic>Pain, Postoperative - drug therapy</topic><topic>Pharmacology. Drug treatments</topic><topic>Postmenopause</topic><topic>Treatment Outcome</topic><topic>Tromethamine - administration & dosage</topic><topic>Tromethamine - analogs & derivatives</topic><topic>Tromethamine - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mercorio, Francesco</creatorcontrib><creatorcontrib>De Simone, Raffaella</creatorcontrib><creatorcontrib>Landi, Paola</creatorcontrib><creatorcontrib>Sarchianaki, Anna</creatorcontrib><creatorcontrib>Tessitore, Giovanni</creatorcontrib><creatorcontrib>Nappi, Carmine</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Maturitas</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mercorio, Francesco</au><au>De Simone, Raffaella</au><au>Landi, Paola</au><au>Sarchianaki, Anna</au><au>Tessitore, Giovanni</au><au>Nappi, Carmine</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Oral dexketoprofen for pain treatment during diagnostic hysteroscopy in postmenopausal women</atitle><jtitle>Maturitas</jtitle><addtitle>Maturitas</addtitle><date>2002-12-10</date><risdate>2002</risdate><volume>43</volume><issue>4</issue><spage>277</spage><epage>281</epage><pages>277-281</pages><issn>0378-5122</issn><eissn>1873-4111</eissn><coden>MATUDK</coden><abstract>Objective: To assess the efficacy of dexketoprofen (DEX) in reducing pain at different stages of the hysteroscopic procedure in comparison with local anaesthesia in menopausal women.
Methods: Menopausal patients affected by uterine bleeding submitted to diagnostic hysteroscopy, were randomised to receive either 25 mg DEX tablet (
n=148) or intracervical injection of 5 ml mepivacaine 2% (
n=150). Pain suffered during the procedure itself and 30, 60, 120 min after, was scored on the 11 point Visual Analogic Scale, recorded and analysed.
Results: No statistical difference were noted during the procedure itself in both groups of treatment. Patients treated with DEX has significantly less postoperative pain.
Conclusions: DEX is not superior to mepivacaine in reducing the discomfort of the procedure but does significantly reduce postoperative pain.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>12468136</pmid><doi>10.1016/S0378-5122(02)00186-X</doi><tpages>5</tpages></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Administration, Oral Analgesics Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Biological and medical sciences Dexketoprofen Female Humans Hysteroscopy Injections Ketoprofen - administration & dosage Ketoprofen - analogs & derivatives Ketoprofen - therapeutic use Medical sciences Mepivacaine - administration & dosage Mepivacaine - therapeutic use Neuropharmacology Pain Pain Measurement Pain, Postoperative - drug therapy Pharmacology. Drug treatments Postmenopause Treatment Outcome Tromethamine - administration & dosage Tromethamine - analogs & derivatives Tromethamine - therapeutic use |
| title | Oral dexketoprofen for pain treatment during diagnostic hysteroscopy in postmenopausal women |
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