The Novel Presenilin-1-associated Protein Is a Proapoptotic Mitochondrial Protein

Recent studies have suggested a possible role for presenilin proteins in apoptotic cell death observed in Alzheimer's disease. The mechanism by which presenilin proteins regulate apoptotic cell death is not well understood. Using the yeast two-hybrid system, we previously isolated a novel prote...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2002-12, Vol.277 (50), p.48913-48922
Hauptverfasser:	Xu, Xuemin, Shi, Yong-chang, Gao, Wei, Mao, Guozhang, Zhao, Guojun, Agrawal, Sudesh, Chisolm, Guy M, Sui, Dexin, Cui, Mei-Zhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Apoptosis - physiology Caspases - metabolism Cell Line Cytochrome c Group - metabolism DNA Primers Enzyme Activation Humans Membrane Proteins - chemistry Membrane Proteins - genetics Membrane Proteins - metabolism Membrane Proteins - physiology Mitochondria - enzymology Mitochondria - metabolism Mitochondrial Proteins - chemistry Mitochondrial Proteins - genetics Mitochondrial Proteins - metabolism Mitochondrial Proteins - physiology Molecular Sequence Data Presenilin-1 Sequence Homology, Amino Acid
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!