Lithium Effects on Inositol Phospholipids and Inositol Phosphates: Evaluation of an In Vivo Model for Assessing Polyphosphoinositide Turnover in Brain

: Administration of lithium chloride to rats injected intracerebrally with [3H]inositol led to time‐ and dose‐dependent increases in levels of labeled inositol monophosphates in brain. Quantitative analysis of the inositol phosphates by ion chromatography revealed 37‐ and 20‐fold increases in the ma...

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Veröffentlicht in:	Journal of neurochemistry 1992-01, Vol.58 (1), p.290-297
Hauptverfasser:	Sun, Grace Y., Navidi, Meena, Yoa, Fu‐Gen, Lin, Teng‐Nan, Orth, Oliver E., Stubbs, Evan B., MacQuarrie, Ronald A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry and metabolism Biological and medical sciences Brain Brain - metabolism Central nervous system Fundamental and applied biological sciences. Psychology In vivo model Inositol phosphates Inositol Phosphates - metabolism Inositol phospholipids Labeled inositol Lithium Lithium - pharmacology Mecamylamine - pharmacology Phosphatidylinositols - metabolism Pilocarpine - pharmacology Polyphosphoinositide turnover Radiotracer technique Rats Rats, Inbred Strains Vertebrates: nervous system and sense organs
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