Characterization of an Anti-Decorin Monoclonal Antibody, and Its Utility

6B6 is a monoclonal antibody raised against a purified small dermatan sulfate proteoglycan from human ovarian fibroma capsule. Although it has been widely used as an anti-decorin monoclonal antibody, its epitope has not yet been characterized at the molecular level. Here, we show that 6B6 is specifi...

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Veröffentlicht in:	Journal of biochemistry (Tokyo) 2002-12, Vol.132 (6), p.997-1002
Hauptverfasser:	Sawada, Hiroo, Shinomura, Tamayuki, Kimata, Koji, Takeuchi, Jun, Tsuji, Takuo, Watanabe, Hideto
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - metabolism antibody Biglycan Cattle Cells, Cultured Decorin Epitopes extracellular matrix Extracellular Matrix Proteins Fibroblasts - cytology Fibroblasts - metabolism Humans Mice Peptides - genetics Peptides - immunology Peptides - metabolism proteoglycan Proteoglycans - genetics Proteoglycans - immunology Proteoglycans - metabolism Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - immunology Recombinant Fusion Proteins - metabolism Skin - cytology Skin - metabolism Skin - pathology
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