Effect of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor Pravastatin on urinary 6 β-hydroxycortisol excretion: a preliminary study

In this preliminary study, the levels of urinary 6 β-hydroxycortisol and urinary free cortisol and the 6 βhydroxycortisol/free cortisol ratio were determined in normal volunteers and in patients with heterozygous familial hypercholesterolemia before and after Pravastatin administration (10 mg/dfor2...

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Veröffentlicht in:	Steroids 1991-12, Vol.56 (12), p.598-600
Hauptverfasser:	Ümit, Karayalçin, Yoshiyu, Takeda, Isamu, Miyamori, Toshio, Morise, Ryoyu, Takeda
Format:	Artikel
Sprache:	eng
Schlagworte:	6 β-hydroxycortisol Adult Biological and medical sciences Cholesterol - blood Errors of metabolism Female hepatic microsomal enzyme induction heterozygous familial hypercholesterolemia HMG-CoA reductase inhibitors Humans Hydrocortisone - analogs & derivatives Hydrocortisone - urine Hydroxymethylglutaryl-CoA Reductase Inhibitors Hyperlipoproteinemia Type II - metabolism Lipids (lysosomal enzyme disorders, storage diseases) Male Medical sciences Metabolic diseases Middle Aged Pravastatin - administration & dosage Pravastatin - pharmacology teroids urinary 6 β-hydroxy cortisol
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