Comparison of PGE2, prostacyclin and leptin release by human adipocytes versus explants of adipose tissue in primary culture

The present studies were designed to investigate the sites of PGE(2), prostacyclin and leptin formation in human adipose tissue. Most of the PGE(2) and prostacyclin formation by adipose tissue explants from obese humans after 48 h in primary culture was due to blood vessels and other tissues not dig...

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Veröffentlicht in:	Prostaglandins, leukotrienes and essential fatty acids leukotrienes and essential fatty acids, 2002-12, Vol.67 (6), p.467-473
Hauptverfasser:	FAIN, J. N, KANU, A, BAHOUTH, S. W, COWAN, G. S. M. JR, HILER, M. L, LEFFLER, C. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - drug effects Adipocytes - metabolism Adipocytes - secretion Adipose Tissue - cytology Adipose Tissue - drug effects Adipose Tissue - metabolism Adipose Tissue - secretion Biological and medical sciences Cells, Cultured Culture Media, Conditioned - chemistry Culture Techniques Cyclooxygenase 2 Dinoprostone - biosynthesis Dinoprostone - secretion Enzyme Induction Epoprostenol - biosynthesis Epoprostenol - secretion Female Fundamental and applied biological sciences. Psychology Humans Interleukin-1 - pharmacology Isoenzymes - metabolism Leptin - biosynthesis Leptin - secretion MAP Kinase Signaling System Membrane Proteins Prostaglandin-Endoperoxide Synthases - metabolism Time Factors Vertebrates: skin, associated glands, phaneres, light organs, various exocrine glands (salt gland, uropygial gland...), adipose tissue, connective tissue
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