Mean pressure obtained by modified rapid pull-through technique used to assess lower esophageal sphincter function

Lower esophageal sphincter pressure, length of sphincter, and contraction of the crural diaphragm are determinants of esophageal function. Mean pressure manometrics in modified rapid pull-through reflects these three factors. Reproducibility and interobserver variability were studied to assess this...

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Veröffentlicht in:Digestive diseases and sciences 2002-11, Vol.47 (11), p.2549-2553
Hauptverfasser: Alonso, P, Estévez, E, Aba, C, González-Conde, B, Yáñez, J, Vázquez-Iglesias, J L
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container_end_page 2553
container_issue 11
container_start_page 2549
container_title Digestive diseases and sciences
container_volume 47
creator Alonso, P
Estévez, E
Aba, C
González-Conde, B
Yáñez, J
Vázquez-Iglesias, J L
description Lower esophageal sphincter pressure, length of sphincter, and contraction of the crural diaphragm are determinants of esophageal function. Mean pressure manometrics in modified rapid pull-through reflects these three factors. Reproducibility and interobserver variability were studied to assess this method's efficacy and were compared with the maximum expiratory pressure in station pull-through in 44 individuals divided into three groups: achalasia, gastroesophageal reflux, and healthy volunteers. Mean pressure in rapid pull-through showed high reproducibility, no significant differences (14.4 +/- 8.4 vs 12.6 +/- 8.2 mm Hg) between two measurements, and a high correlation coefficient (r = 0.9). Interobserver variability was lower than that seen for maximum expiratory pressure (P < 0.001). Mean pressure was lower than maximum expiratory pressure in patients with achalasia (21.1 +/- 7 vs 30.7 +/- 8.6 mm Hg). Both methods showed identical sensitivity to establish a hypotensive sphincter in patients with reflux (73%). We think that mean pressure obtained by rapid pull-through is a good methodology to assess lower esophageal sphincter competence. It is rapid, simple, shows good reproducibility and low interobserver variability, and is clinically valid.
doi_str_mv 10.1023/A:1020576529685
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subjects Adolescent
Adult
Aged
Esophageal Achalasia - physiopathology
Esophagogastric Junction - physiology
Female
Gastroesophageal Reflux - physiopathology
Humans
Male
Manometry - methods
Middle Aged
Observer Variation
title Mean pressure obtained by modified rapid pull-through technique used to assess lower esophageal sphincter function
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