Regulation of myelin basic protein-specific helper T cells in multiple sclerosis: Generation of suppressor T cell lines

Suppressor T cell (Ts) lines specific for myelin basic protein (MBP)-reactive helper T cell (Th) clones were generated from two patients with multiple sclerosis (MS) following a primary culture of peripheral blood mononuclear cells (PBMC) with MBP and cyclosporine A (CsA). These suppressor T cell li...

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Veröffentlicht in:	Cellular immunology 1992, Vol.139 (1), p.118-130
Hauptverfasser:	Jingwu, Zhang, Schreurs, Marleen, Medaer, Robert, Raus, Jef C.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Differentiation, T-Lymphocyte - analysis CD3 Complex CD4-Positive T-Lymphocytes - immunology CD8 Antigens - analysis Cells, Cultured Clone Cells Cyclosporine - pharmacology Cytotoxicity, Immunologic HLA-DR Antigens - analysis Humans In Vitro Techniques Lymphocyte Activation Lymphokines - physiology Multiple Sclerosis - immunology Myelin Basic Protein - immunology Receptors, Antigen, T-Cell - analysis T-Lymphocyte Subsets - immunology T-Lymphocytes, Helper-Inducer - immunology T-Lymphocytes, Regulatory - immunology
Online-Zugang:	Volltext
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