Further case of paroxysmal exercise-induced dystonia and some insights into pathogenesis
Cerebrospinal fluid (CSF) analysis of pterin and monamine metabolites was performed before and after an attack in a patient with paroxysmal exercise‐induced dystonia. A twofold increase in CSF homovanillic acid and 5‐hydroxyindoleacetic acid after an attack was measured. This finding lends support t...
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Veröffentlicht in: | Movement disorders 2002-11, Vol.17 (6), p.1386-1387 |
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creator | Barnett, Michael H. Jarman, Paul R. Heales, Simon J.R. Bhatia, Kailash P. |
description | Cerebrospinal fluid (CSF) analysis of pterin and monamine metabolites was performed before and after an attack in a patient with paroxysmal exercise‐induced dystonia. A twofold increase in CSF homovanillic acid and 5‐hydroxyindoleacetic acid after an attack was measured. This finding lends support to the hypothesis that increased dopaminergic transmission contributes to the clinical features of the hyperkinetic movement disorders. © 2002 Movement Disorder Society |
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This finding lends support to the hypothesis that increased dopaminergic transmission contributes to the clinical features of the hyperkinetic movement disorders. © 2002 Movement Disorder Society</description><subject>Adult</subject><subject>cerebrospinal fluid</subject><subject>dopamine</subject><subject>Dopamine - physiology</subject><subject>Dystonia - diagnosis</subject><subject>Dystonia - physiopathology</subject><subject>Exercise - physiology</subject><subject>homovanillic acid</subject><subject>Homovanillic Acid - cerebrospinal fluid</subject><subject>Humans</subject><subject>hydroxyindoleacetic acid</subject><subject>Hydroxyindoleacetic Acid - cerebrospinal fluid</subject><subject>Male</subject><subject>Neurologic Examination</subject><subject>paroxysmal exercise-induced dystonia</subject><subject>Synaptic Transmission - physiology</subject><issn>0885-3185</issn><issn>1531-8257</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMFu1DAQhi0EotvCgRdAOSFxCPXYsZMcoWVbpAKHBYG4WF570jUk8eJJxO7b17ALnBCnmcP3_5r5GHsC_AVwLs4HT3kRLdxjC1ASykao-j5b8KZRpYRGnbBToq-cAyjQD9kJiEor3sKCfV7OadpgKpwlLGJXbG2Kuz0Nti9wh8kFwjKMfnboC7-nKY7BFnb0BcUBizBSuN1MlJcp5uy0ibc4IgV6xB50tid8fJxn7OPy9YeL6_Lm_dWbi5c3pZMtz5dW4Oy68-BELbX2Uun8Um2F8LLy3gu_5k3dIdrGidZLgcK3NcBa60pXspVn7Nmhd5vi9xlpMkMgh31vR4wzmTr3tlLw_4Iiy5Gtggw-P4AuRaKEndmmMNi0N8DNT98m-za_fGf26bF0Xg_o_5JHwRk4PwA_Qo_7fzeZt5er35XlIRFowt2fhE3fjK5lrcynd1dmef1q1Vx-AbOSd82dmV8</recordid><startdate>200211</startdate><enddate>200211</enddate><creator>Barnett, Michael H.</creator><creator>Jarman, Paul R.</creator><creator>Heales, Simon J.R.</creator><creator>Bhatia, Kailash P.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7TS</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>200211</creationdate><title>Further case of paroxysmal exercise-induced dystonia and some insights into pathogenesis</title><author>Barnett, Michael H. ; Jarman, Paul R. ; Heales, Simon J.R. ; Bhatia, Kailash P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3901-841cabfd1c27366d3561007a22d34ddd2db087feea8c29d32e2d9711b66464393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>cerebrospinal fluid</topic><topic>dopamine</topic><topic>Dopamine - physiology</topic><topic>Dystonia - diagnosis</topic><topic>Dystonia - physiopathology</topic><topic>Exercise - physiology</topic><topic>homovanillic acid</topic><topic>Homovanillic Acid - cerebrospinal fluid</topic><topic>Humans</topic><topic>hydroxyindoleacetic acid</topic><topic>Hydroxyindoleacetic Acid - cerebrospinal fluid</topic><topic>Male</topic><topic>Neurologic Examination</topic><topic>paroxysmal exercise-induced dystonia</topic><topic>Synaptic Transmission - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barnett, Michael H.</creatorcontrib><creatorcontrib>Jarman, Paul R.</creatorcontrib><creatorcontrib>Heales, Simon J.R.</creatorcontrib><creatorcontrib>Bhatia, Kailash P.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>Movement disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barnett, Michael H.</au><au>Jarman, Paul R.</au><au>Heales, Simon J.R.</au><au>Bhatia, Kailash P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Further case of paroxysmal exercise-induced dystonia and some insights into pathogenesis</atitle><jtitle>Movement disorders</jtitle><addtitle>Mov. 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subjects | Adult cerebrospinal fluid dopamine Dopamine - physiology Dystonia - diagnosis Dystonia - physiopathology Exercise - physiology homovanillic acid Homovanillic Acid - cerebrospinal fluid Humans hydroxyindoleacetic acid Hydroxyindoleacetic Acid - cerebrospinal fluid Male Neurologic Examination paroxysmal exercise-induced dystonia Synaptic Transmission - physiology |
title | Further case of paroxysmal exercise-induced dystonia and some insights into pathogenesis |
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