Plasma-mediated ablation of corneal tissue at 1053 nm using a Nd:YLF oscillator/regenerative amplifier laser

Plasma‐mediated ablations were performed on human donor corneas with a short pulsed Nd:YLF laser system at 1053 nm. The pulses were 60 psec in duration at a repetition rate of 1.0 kHz. The laser beam was oriented perpendicular to the cornea surface. The threshold energy densities for ablation of epi...

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Veröffentlicht in:Lasers in surgery and medicine 1991, Vol.11 (5), p.426-431
Hauptverfasser: Niemz, Mark H., Klancnik, Edward G., Bille, Josef F.
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container_title Lasers in surgery and medicine
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creator Niemz, Mark H.
Klancnik, Edward G.
Bille, Josef F.
description Plasma‐mediated ablations were performed on human donor corneas with a short pulsed Nd:YLF laser system at 1053 nm. The pulses were 60 psec in duration at a repetition rate of 1.0 kHz. The laser beam was oriented perpendicular to the cornea surface. The threshold energy densities for ablation of epithelium, Bowman's membrane and stroma were measured. They were 6.1±1.8 J/cm2, 21.0±5.1 J/cm2 and 10.4±1.8 J/cm2, respectively. The mean rate of tissue removal at the stromal energy density threshold was about 1 μm per pulse. The walls of the laser excisions were smooth with distortions of less than 1 μm. A new quantitative model of plasma‐mediated ablation is introduced and found to closely predict the observed results. Based on the promising nature of the experimental data further investigations are planned in the use of a mode locked Nd:YLF laser as an alternative to excimer lasers for refractive corneal surgery.
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Med</addtitle><description>Plasma‐mediated ablations were performed on human donor corneas with a short pulsed Nd:YLF laser system at 1053 nm. The pulses were 60 psec in duration at a repetition rate of 1.0 kHz. The laser beam was oriented perpendicular to the cornea surface. The threshold energy densities for ablation of epithelium, Bowman's membrane and stroma were measured. They were 6.1±1.8 J/cm2, 21.0±5.1 J/cm2 and 10.4±1.8 J/cm2, respectively. The mean rate of tissue removal at the stromal energy density threshold was about 1 μm per pulse. The walls of the laser excisions were smooth with distortions of less than 1 μm. A new quantitative model of plasma‐mediated ablation is introduced and found to closely predict the observed results. Based on the promising nature of the experimental data further investigations are planned in the use of a mode locked Nd:YLF laser as an alternative to excimer lasers for refractive corneal surgery.</description><subject>Biological and medical sciences</subject><subject>Cornea - surgery</subject><subject>Corneal Stroma - surgery</subject><subject>corneal surgery</subject><subject>Energy Transfer</subject><subject>Equipment Design</subject><subject>Humans</subject><subject>Lasers</subject><subject>Light Coagulation - instrumentation</subject><subject>Light Coagulation - methods</subject><subject>Medical sciences</subject><subject>Nd:YLF laser</subject><subject>Neodymium</subject><subject>plasma-mediated ablation</subject><subject>Regression Analysis</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the eye and orbit</topic><topic>Yttrium</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Niemz, Mark H.</creatorcontrib><creatorcontrib>Klancnik, Edward G.</creatorcontrib><creatorcontrib>Bille, Josef F.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Lasers in surgery and medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Niemz, Mark H.</au><au>Klancnik, Edward G.</au><au>Bille, Josef F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Plasma-mediated ablation of corneal tissue at 1053 nm using a Nd:YLF oscillator/regenerative amplifier laser</atitle><jtitle>Lasers in surgery and medicine</jtitle><addtitle>Lasers Surg. Med</addtitle><date>1991</date><risdate>1991</risdate><volume>11</volume><issue>5</issue><spage>426</spage><epage>431</epage><pages>426-431</pages><issn>0196-8092</issn><eissn>1096-9101</eissn><coden>LSMEDI</coden><abstract>Plasma‐mediated ablations were performed on human donor corneas with a short pulsed Nd:YLF laser system at 1053 nm. The pulses were 60 psec in duration at a repetition rate of 1.0 kHz. The laser beam was oriented perpendicular to the cornea surface. The threshold energy densities for ablation of epithelium, Bowman's membrane and stroma were measured. They were 6.1±1.8 J/cm2, 21.0±5.1 J/cm2 and 10.4±1.8 J/cm2, respectively. The mean rate of tissue removal at the stromal energy density threshold was about 1 μm per pulse. The walls of the laser excisions were smooth with distortions of less than 1 μm. A new quantitative model of plasma‐mediated ablation is introduced and found to closely predict the observed results. Based on the promising nature of the experimental data further investigations are planned in the use of a mode locked Nd:YLF laser as an alternative to excimer lasers for refractive corneal surgery.</abstract><cop>New York</cop><pub>John Wiley &amp; Sons, Inc</pub><pmid>1816477</pmid><doi>10.1002/lsm.1900110507</doi><tpages>6</tpages></addata></record>
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source MEDLINE; Wiley Online Library All Journals
subjects Biological and medical sciences
Cornea - surgery
Corneal Stroma - surgery
corneal surgery
Energy Transfer
Equipment Design
Humans
Lasers
Light Coagulation - instrumentation
Light Coagulation - methods
Medical sciences
Nd:YLF laser
Neodymium
plasma-mediated ablation
Regression Analysis
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the eye and orbit
Yttrium
title Plasma-mediated ablation of corneal tissue at 1053 nm using a Nd:YLF oscillator/regenerative amplifier laser
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