Antihepatitis B response to hepatitis B vaccine administered simultaneously with tetanus toxoid in nonresponder individuals

In this prospective study, our aim was to test the effect of simultaneous administration of preS2 and S containing recombinant hepatitis B vaccine (S2SRHB) with tetanus toxoid (TT) to the individuals who did not respond after three doses of hepatitis B vaccine previously. There were three groups (he...

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Veröffentlicht in:Vaccine 2002-12, Vol.21 (3), p.243-246
Hauptverfasser: Sönmez, Emine, Sönmez, Ali Suha, Bayindir, Yaşar, Coskun, Diler, Aritürk, Sedat
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container_issue 3
container_start_page 243
container_title Vaccine
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creator Sönmez, Emine
Sönmez, Ali Suha
Bayindir, Yaşar
Coskun, Diler
Aritürk, Sedat
description In this prospective study, our aim was to test the effect of simultaneous administration of preS2 and S containing recombinant hepatitis B vaccine (S2SRHB) with tetanus toxoid (TT) to the individuals who did not respond after three doses of hepatitis B vaccine previously. There were three groups (healthy individuals, pregnant women, hemodialysis patients), each was divided into two subgroups as groups A and B. Group A received S2SRHB+TT and group B received only S2SRHB. We found that in groups receiving both vaccines, both seroconversion rate and antibody titer level were significantly higher ( P
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subjects Adolescent
Adult
Age
Antibodies, Viral - blood
Biological and medical sciences
Female
Fundamental and applied biological sciences. Psychology
Hemodialysis
Hepatitis
Hepatitis B - immunology
Hepatitis B - prevention & control
Hepatitis B vaccine
Hepatitis B Vaccines - administration & dosage
Hepatitis B Vaccines - immunology
Hepatitis B virus
Humans
Injections
Male
Microbiology
Middle Aged
Nonresponder
Prospective Studies
Response rates
Tetanus
Tetanus toxoid
Tetanus Toxoid - administration & dosage
Tetanus Toxoid - immunology
Vaccination
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies
Vaccines, Combined - administration & dosage
Vaccines, Combined - immunology
Vaccines, Synthetic - administration & dosage
Vaccines, Synthetic - immunology
Virology
title Antihepatitis B response to hepatitis B vaccine administered simultaneously with tetanus toxoid in nonresponder individuals
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