Cytogenetic, FISH, and molecular studies in a case of B-cell chronic lymphocytic leukemia with karyotypic evolution

: We report the clinical, cytogenetic, fluorescence in situ hybridization (FISH) and molecular findings in a 54‐yr‐old male patient diagnosed with B‐cell chronic lymphocytic leukemia (B‐CLL), who showed progression to a diffuse large B‐cell lymphoma (Richter's syndrome). Genetic studies were p...

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Veröffentlicht in:	European journal of haematology 2002-11, Vol.69 (5-6), p.309-314
Hauptverfasser:	Chena, Christian, Cerretini, Roxana, Noriega, María Fernanda, Narbaitz, Marina, Scolnik, Mariano, Palacios, María Fernanda, Neme, Daniela, Bruno, Salvador, Slavutsky, Irma
Format:	Artikel
Sprache:	eng
Schlagworte:	bcl-2 gene Biological and medical sciences chronic lymphocytic leukemia Cytogenetic Analysis - methods Disease Progression FISH analysis Gene Deletion Gene Rearrangement Genes, p53 Hematologic and hematopoietic diseases Humans In Situ Hybridization, Fluorescence karyotypic evolution Karyotyping Leukemia, Lymphocytic, Chronic, B-Cell - genetics Leukemia, Lymphocytic, Chronic, B-Cell - pathology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Middle Aged p53 deletion Polymerase Chain Reaction Richter's syndrome Tropical medicine
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