Long-term experience with descending aortic dissection: The complication-specific approach
We analyzed long-term results in 71 patients (45 men and 26 women) treated over 17 years for documented descending aortic dissection. Forty-nine patients were treated medically and 22, surgically. Actuarial survival was 65% at 1 year, 57% at 3 years, 50% at 5 years, and 28% at 10 years for the whole...
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Veröffentlicht in: | The Annals of thoracic surgery 1992-01, Vol.53 (1), p.11-21 |
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creator | Elefteriades, John A. Hartleroad, J. Gusberg, R.J. Salazar, A.M. Black, H.R. Kopf, G.S. Baldwin, John C. Hammond, Graeme L. |
description | We analyzed long-term results in 71 patients (45 men and 26 women) treated over 17 years for documented descending aortic dissection. Forty-nine patients were treated medically and 22, surgically. Actuarial survival was 65% at 1 year, 57% at 3 years, 50% at 5 years, and 28% at 10 years for the whole group. For the group treated medically, survival was 73%, 63%, 58%, and 25% at 1 year, 3 years, 5 years, and 10 years, respectively, and for the group treated surgically, 47%, 40%, and 28% at 1 year, 3 years, and 5 years, respectively. Ten (20.4%) of the 49 medically treated patients died early (5 of rupture), and 14 (28.6%) died late (8 of dissection). Five medically treated patients crossed over to surgical management for complications of dissection. Among the surgically treated patients, 6 underwent standard graft replacement of the proximal descending aorta, 8 underwent the fenestration procedure (with a standardized retroperitoneal abdominal approach), and 4 underwent the thromboexclusion operation. Specific analysis of fenestration in 14 patients (including some with persistent descending aortic dissection after replacement of the ascending aorta for dissection) found it to be safe and effective. Actuarial survival after fenestration was 77%, 77%, and 53% at 1 year, 3 years, and 5 years, respectively. Thromboexclusion was found effective, and postoperative studio confirmed thrombosis of the descending aorta with preservation of the lowest intercostal arteries. Fifteen of the 21 surviving medically treated patients agreed to return for follow-up imaging. Nine had thrombosis of the false lumen. An interesting radiographic finding was (hat 4 of the 15 restudied patients had a saccular aneurysm in the aorta at the level of the left subclavian artery. We recommend a complication-specific approach to the management of descending aortic dissection. Uncomplicated dissection is treated medically, whereas complicated dissection is treated surgically, with realized rupture treated by standard graft replacement, limb ischemia treated by fenestration, and enlargement or impending rupture treated by thromboexclusion. |
doi_str_mv | 10.1016/0003-4975(92)90752-P |
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Forty-nine patients were treated medically and 22, surgically. Actuarial survival was 65% at 1 year, 57% at 3 years, 50% at 5 years, and 28% at 10 years for the whole group. For the group treated medically, survival was 73%, 63%, 58%, and 25% at 1 year, 3 years, 5 years, and 10 years, respectively, and for the group treated surgically, 47%, 40%, and 28% at 1 year, 3 years, and 5 years, respectively. Ten (20.4%) of the 49 medically treated patients died early (5 of rupture), and 14 (28.6%) died late (8 of dissection). Five medically treated patients crossed over to surgical management for complications of dissection. Among the surgically treated patients, 6 underwent standard graft replacement of the proximal descending aorta, 8 underwent the fenestration procedure (with a standardized retroperitoneal abdominal approach), and 4 underwent the thromboexclusion operation. Specific analysis of fenestration in 14 patients (including some with persistent descending aortic dissection after replacement of the ascending aorta for dissection) found it to be safe and effective. Actuarial survival after fenestration was 77%, 77%, and 53% at 1 year, 3 years, and 5 years, respectively. Thromboexclusion was found effective, and postoperative studio confirmed thrombosis of the descending aorta with preservation of the lowest intercostal arteries. Fifteen of the 21 surviving medically treated patients agreed to return for follow-up imaging. Nine had thrombosis of the false lumen. An interesting radiographic finding was (hat 4 of the 15 restudied patients had a saccular aneurysm in the aorta at the level of the left subclavian artery. We recommend a complication-specific approach to the management of descending aortic dissection. Uncomplicated dissection is treated medically, whereas complicated dissection is treated surgically, with realized rupture treated by standard graft replacement, limb ischemia treated by fenestration, and enlargement or impending rupture treated by thromboexclusion.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/0003-4975(92)90752-P</identifier><identifier>PMID: 1728218</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Aneurysm, Dissecting - diagnosis ; Aneurysm, Dissecting - mortality ; Aneurysm, Dissecting - surgery ; Aorta, Thoracic - diagnostic imaging ; Aorta, Thoracic - surgery ; Aortic Aneurysm - diagnosis ; Aortic Aneurysm - mortality ; Aortic Aneurysm - surgery ; Aortic Rupture - mortality ; Cause of Death ; Female ; Follow-Up Studies ; Humans ; Ischemia - etiology ; Ischemia - surgery ; Kidney - blood supply ; Leg - blood supply ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Postoperative Complications - diagnosis ; Postoperative Complications - mortality ; Postoperative Complications - surgery ; Radiography ; Spinal Cord - blood supply ; Survival Rate</subject><ispartof>The Annals of thoracic surgery, 1992-01, Vol.53 (1), p.11-21</ispartof><rights>1992 The Society of Thoracic Surgeons</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c488t-dbdc4b28f9255f4c34dd2e83e4dc91e7d3ceecfbea43b5a8d852a6212baf44273</citedby><cites>FETCH-LOGICAL-c488t-dbdc4b28f9255f4c34dd2e83e4dc91e7d3ceecfbea43b5a8d852a6212baf44273</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1728218$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Elefteriades, John A.</creatorcontrib><creatorcontrib>Hartleroad, J.</creatorcontrib><creatorcontrib>Gusberg, R.J.</creatorcontrib><creatorcontrib>Salazar, A.M.</creatorcontrib><creatorcontrib>Black, H.R.</creatorcontrib><creatorcontrib>Kopf, G.S.</creatorcontrib><creatorcontrib>Baldwin, John C.</creatorcontrib><creatorcontrib>Hammond, Graeme L.</creatorcontrib><title>Long-term experience with descending aortic dissection: The complication-specific approach</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>We analyzed long-term results in 71 patients (45 men and 26 women) treated over 17 years for documented descending aortic dissection. Forty-nine patients were treated medically and 22, surgically. Actuarial survival was 65% at 1 year, 57% at 3 years, 50% at 5 years, and 28% at 10 years for the whole group. For the group treated medically, survival was 73%, 63%, 58%, and 25% at 1 year, 3 years, 5 years, and 10 years, respectively, and for the group treated surgically, 47%, 40%, and 28% at 1 year, 3 years, and 5 years, respectively. Ten (20.4%) of the 49 medically treated patients died early (5 of rupture), and 14 (28.6%) died late (8 of dissection). Five medically treated patients crossed over to surgical management for complications of dissection. Among the surgically treated patients, 6 underwent standard graft replacement of the proximal descending aorta, 8 underwent the fenestration procedure (with a standardized retroperitoneal abdominal approach), and 4 underwent the thromboexclusion operation. Specific analysis of fenestration in 14 patients (including some with persistent descending aortic dissection after replacement of the ascending aorta for dissection) found it to be safe and effective. Actuarial survival after fenestration was 77%, 77%, and 53% at 1 year, 3 years, and 5 years, respectively. Thromboexclusion was found effective, and postoperative studio confirmed thrombosis of the descending aorta with preservation of the lowest intercostal arteries. Fifteen of the 21 surviving medically treated patients agreed to return for follow-up imaging. Nine had thrombosis of the false lumen. An interesting radiographic finding was (hat 4 of the 15 restudied patients had a saccular aneurysm in the aorta at the level of the left subclavian artery. We recommend a complication-specific approach to the management of descending aortic dissection. Uncomplicated dissection is treated medically, whereas complicated dissection is treated surgically, with realized rupture treated by standard graft replacement, limb ischemia treated by fenestration, and enlargement or impending rupture treated by thromboexclusion.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aneurysm, Dissecting - diagnosis</subject><subject>Aneurysm, Dissecting - mortality</subject><subject>Aneurysm, Dissecting - surgery</subject><subject>Aorta, Thoracic - diagnostic imaging</subject><subject>Aorta, Thoracic - surgery</subject><subject>Aortic Aneurysm - diagnosis</subject><subject>Aortic Aneurysm - mortality</subject><subject>Aortic Aneurysm - surgery</subject><subject>Aortic Rupture - mortality</subject><subject>Cause of Death</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Ischemia - etiology</subject><subject>Ischemia - surgery</subject><subject>Kidney - blood supply</subject><subject>Leg - blood supply</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Postoperative Complications - diagnosis</subject><subject>Postoperative Complications - mortality</subject><subject>Postoperative Complications - surgery</subject><subject>Radiography</subject><subject>Spinal Cord - blood supply</subject><subject>Survival Rate</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kElPwzAQhS0EKmX5ByDlhOAQsB27cTggoYpNqkQP5cLFcuxJa5QNO2X59zhNBTdOtue9eTP-EDoh-JJgMrnCGCcxy1J-ntGLDKecxvMdNCY8XCaUZ7to_GvZRwfev4UnDfIIjUhKBSVijF5nTb2MO3BVBF8tOAu1hujTdqvIgNdQG1svI9W4zurIWO9Bd7apr6PFCiLdVG1pteorsW9B2yK4VNu6RunVEdorVOnheHseopf7u8X0MZ49PzxNb2exZkJ0scmNZjkVRUY5L5hOmDEURALM6IxAahINoIscFEtyroQRnKoJJTRXBWM0TQ7R2ZAbxr6vwXeysmHzslQ1NGsvU5pSzERvZINRu8Z7B4Vsna2U-5YEyx6p7HnJnpfMqNwglfPQdrrNX-cVmL-mgWHQbwYdwic_LDjp9QajsS7Qkqax_w_4AXiciAc</recordid><startdate>19920101</startdate><enddate>19920101</enddate><creator>Elefteriades, John A.</creator><creator>Hartleroad, J.</creator><creator>Gusberg, R.J.</creator><creator>Salazar, A.M.</creator><creator>Black, H.R.</creator><creator>Kopf, G.S.</creator><creator>Baldwin, John C.</creator><creator>Hammond, Graeme L.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19920101</creationdate><title>Long-term experience with descending aortic dissection: The complication-specific approach</title><author>Elefteriades, John A. ; Hartleroad, J. ; Gusberg, R.J. ; Salazar, A.M. ; Black, H.R. ; Kopf, G.S. ; Baldwin, John C. ; Hammond, Graeme L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c488t-dbdc4b28f9255f4c34dd2e83e4dc91e7d3ceecfbea43b5a8d852a6212baf44273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aneurysm, Dissecting - diagnosis</topic><topic>Aneurysm, Dissecting - mortality</topic><topic>Aneurysm, Dissecting - surgery</topic><topic>Aorta, Thoracic - diagnostic imaging</topic><topic>Aorta, Thoracic - surgery</topic><topic>Aortic Aneurysm - diagnosis</topic><topic>Aortic Aneurysm - mortality</topic><topic>Aortic Aneurysm - surgery</topic><topic>Aortic Rupture - mortality</topic><topic>Cause of Death</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Ischemia - etiology</topic><topic>Ischemia - surgery</topic><topic>Kidney - blood supply</topic><topic>Leg - blood supply</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Postoperative Complications - diagnosis</topic><topic>Postoperative Complications - mortality</topic><topic>Postoperative Complications - surgery</topic><topic>Radiography</topic><topic>Spinal Cord - blood supply</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Elefteriades, John A.</creatorcontrib><creatorcontrib>Hartleroad, J.</creatorcontrib><creatorcontrib>Gusberg, R.J.</creatorcontrib><creatorcontrib>Salazar, A.M.</creatorcontrib><creatorcontrib>Black, H.R.</creatorcontrib><creatorcontrib>Kopf, G.S.</creatorcontrib><creatorcontrib>Baldwin, John C.</creatorcontrib><creatorcontrib>Hammond, Graeme L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Elefteriades, John A.</au><au>Hartleroad, J.</au><au>Gusberg, R.J.</au><au>Salazar, A.M.</au><au>Black, H.R.</au><au>Kopf, G.S.</au><au>Baldwin, John C.</au><au>Hammond, Graeme L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term experience with descending aortic dissection: The complication-specific approach</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>1992-01-01</date><risdate>1992</risdate><volume>53</volume><issue>1</issue><spage>11</spage><epage>21</epage><pages>11-21</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><abstract>We analyzed long-term results in 71 patients (45 men and 26 women) treated over 17 years for documented descending aortic dissection. Forty-nine patients were treated medically and 22, surgically. Actuarial survival was 65% at 1 year, 57% at 3 years, 50% at 5 years, and 28% at 10 years for the whole group. For the group treated medically, survival was 73%, 63%, 58%, and 25% at 1 year, 3 years, 5 years, and 10 years, respectively, and for the group treated surgically, 47%, 40%, and 28% at 1 year, 3 years, and 5 years, respectively. Ten (20.4%) of the 49 medically treated patients died early (5 of rupture), and 14 (28.6%) died late (8 of dissection). Five medically treated patients crossed over to surgical management for complications of dissection. Among the surgically treated patients, 6 underwent standard graft replacement of the proximal descending aorta, 8 underwent the fenestration procedure (with a standardized retroperitoneal abdominal approach), and 4 underwent the thromboexclusion operation. Specific analysis of fenestration in 14 patients (including some with persistent descending aortic dissection after replacement of the ascending aorta for dissection) found it to be safe and effective. Actuarial survival after fenestration was 77%, 77%, and 53% at 1 year, 3 years, and 5 years, respectively. Thromboexclusion was found effective, and postoperative studio confirmed thrombosis of the descending aorta with preservation of the lowest intercostal arteries. Fifteen of the 21 surviving medically treated patients agreed to return for follow-up imaging. Nine had thrombosis of the false lumen. An interesting radiographic finding was (hat 4 of the 15 restudied patients had a saccular aneurysm in the aorta at the level of the left subclavian artery. We recommend a complication-specific approach to the management of descending aortic dissection. Uncomplicated dissection is treated medically, whereas complicated dissection is treated surgically, with realized rupture treated by standard graft replacement, limb ischemia treated by fenestration, and enlargement or impending rupture treated by thromboexclusion.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>1728218</pmid><doi>10.1016/0003-4975(92)90752-P</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Aged, 80 and over Aneurysm, Dissecting - diagnosis Aneurysm, Dissecting - mortality Aneurysm, Dissecting - surgery Aorta, Thoracic - diagnostic imaging Aorta, Thoracic - surgery Aortic Aneurysm - diagnosis Aortic Aneurysm - mortality Aortic Aneurysm - surgery Aortic Rupture - mortality Cause of Death Female Follow-Up Studies Humans Ischemia - etiology Ischemia - surgery Kidney - blood supply Leg - blood supply Magnetic Resonance Imaging Male Middle Aged Postoperative Complications - diagnosis Postoperative Complications - mortality Postoperative Complications - surgery Radiography Spinal Cord - blood supply Survival Rate |
title | Long-term experience with descending aortic dissection: The complication-specific approach |
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