Albugranin, a recombinant human granulocyte colony stimulating factor (G-CSF) genetically fused to recombinant human albumin induces prolonged myelopoietic effects in mice and monkeys

Albugranin fusion protein is recombinant granulocyte colony stimulating factor (rG-CSF) genetically fused at its N-terminus to the C-terminus of recombinant serum human albumin and is expected to have a relatively long half-life compared with rG-CSF alone. In this study, the pharmacodynamics and pha...

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Veröffentlicht in:Pharmaceutical research 2002-11, Vol.19 (11), p.1720-1729
Hauptverfasser: HALPERN, Wendy, RICCOBENE, Todd A, GRZEGORZEWSKI, Krzysztof J, AGOSTINI, Heidi, BAKER, Kevin, STOLOW, David, GU, Mi-Li, HIRSCH, Jonathan, MAHONEY, Angela, CARRELL, Jeffrey, BOYD, Ernest
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Sprache:eng
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