ATP-evoked calcium signal stimulates protein phosphorylation/dephosphorylation in astrocytes

Extracellular adenosine 5′-triphosphate (ATP)-evoked increases in intracellular calcium and the consequent stimulation of calcium-mediated protein phosphorylation systems were investigated in primary cultures of rat cerebral cortical astrocytes. Measurement of calcium responses in fura-2-loaded astr...

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Veröffentlicht in:	Brain research 1991-12, Vol.566 (1), p.89-94
Hauptverfasser:	Neary, J.T., Laskey, R., van Breemen, C., Blicharska, J., Norenberg, L.O.B., Norenberg, M.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine 5′-triphosphate Adenosine Triphosphate - pharmacology Animals Animals, Newborn Astrocyte Astrocytes - drug effects Astrocytes - metabolism Astrocytes - physiology Autoradiography Biological and medical sciences Calcium Calcium - physiology Cells, Cultured Cytosol - metabolism Electrophoresis, Polyacrylamide Gel Fundamental and applied biological sciences. Psychology Ionomycin - pharmacology Isolated neuron and nerve. Neuroglia Kinetics Molecular Weight Nerve Tissue Proteins - isolation & purification Nerve Tissue Proteins - metabolism Phosphates - metabolism Phosphoproteins - isolation & purification Phosphoproteins - metabolism Phosphorus Radioisotopes Phosphorylation Protein phosphorylation Purinergic receptor Rats Vertebrates: nervous system and sense organs
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