Synthesis and proaggregatory activity of 1- O-(2-methyloctadecyl)-2- O-acetyl- rac-glycero-3-phosphocholine

Racemic 1- O-(2-methyloctadecyl)-2- O-acetyl-glycero-3-phosphocholine, a branched chain PAF species, was prepared by chemical synthesis and investigated for biological activity on human blood platelets in vitro. The synthesis started from 2- O-benzylglycerol and 2-methyloctadecyl-1-methyl sulfonate...

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Veröffentlicht in:	Chemistry and physics of lipids 1991-11, Vol.60 (1), p.77-82
Hauptverfasser:	Schmid, B., Ostermann, G., Kertscher, H.-P.
Format:	Artikel
Sprache:	eng
Schlagworte:	chemical synthesis Chemistry Exact sciences and technology human platelet aggregation Humans Lipids Molecular Structure Organic chemistry Platelet Activating Factor - analogs & derivatives Platelet Activating Factor - chemical synthesis Platelet Activating Factor - metabolism Platelet Activating Factor - pharmacology Platelet Aggregation - drug effects platelet-activating factor (PAF) species Preparations and properties Protein Binding
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