ALEX (artificial liver for extracorporeal xenoassistance): a new bioreactor containing a porcine autologous biomatrix as hepatocyte support. Preliminary results in an ex vivo experimental model

Long-term maintenance of viability and expression of differentiated hepatocyte function is crucial for bioartificial liver support. We developed a new bioreactor design (ALEX), associated with a new extracellular autologous hepatocyte biomatrix (Porcine Autologous Biomatrix - PBM) support. To test t...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of artificial organs 2002-10, Vol.25 (10), p.960-965
Hauptverfasser:	Ambrosino, G, Varotto, S, Basso, S, Galavotti, D, Cecchetto, A, Carraro, P, Naso, A, De Silvestro, G, Plebani, M, Giron, G, Abatangelo, G, Donato, D, Braga, G P, Cestrone, A, Marrelli, L, Trombetta, M, Lorenzelli, V, Picardi, A, Valente, M L, Palu, G, Colantoni, A, Van Thiel, D, Ricordi, C, D'Amico, D F
Format:	Artikel
Sprache:	eng
Schlagworte:	Ammonia - blood Animals Bilirubin - blood Bioreactors Extracorporeal Circulation Hepatocytes Humans Lidocaine - blood Liver, Artificial Prothrombin Time Swine Tissue Engineering
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!