A microarray-based, integrated approach to identify novel regulators of cancer drug response and apoptosis

DNA microarrays are powerful tools for the analysis of gene expression on a genomic scale. The importance of individual regulatory events for the process under study can however not be deduced unequivocally without additional experiments. We devised a strategy to identify central regulators of cance...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oncogene 2002-11, Vol.21 (54), p.8361-8371
Hauptverfasser:	BRACHAT, Arndt, PIERRAT, Benoit, XYNOS, Alexandros, BRECHT, Karin, SIMONEN, Marjo, BRÜNGGER, Adrian, HEIM, Jutta
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimitotic agents Antineoplastic agents Antineoplastic Agents - pharmacology Apoptosis Apoptosis - drug effects Apoptosis - genetics Base Sequence Bcl-2 protein Biological and medical sciences Camptothecin Cancer therapies Caspase Cell cycle Cell death Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Cisplatin Cloning, Molecular Cytokines Dihydrofolate reductase DNA microarrays DNA, Complementary Dosage and administration Ectopic expression Experiments Expressed Sequence Tags Flow Cytometry Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Profiling Genetic aspects Hemoglobin Integrated approach Interleukin 3 Interleukin-3 - pharmacology Kinases Lymphocytes B Methotrexate Mice Molecular and cellular biology Molecular Sequence Data Oligonucleotide Array Sequence Analysis Paclitaxel Phenotype Physiological aspects Staurosporine Staurosporine - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!