Induction of angiogenesis in a mouse model using engineered transcription factors

The relationship between the structure of zinc-finger protein (ZFP) transcription factors and DNA sequence binding specificity has been extensively studied 1 . Advances in this field have made it possible to design ZFPs de novo that will bind to specific targeted DNA sequences 2 , 3 , 4 , 5 , 6 , 7...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature medicine 2002-12, Vol.8 (12), p.1427-1432
Hauptverfasser:	Giordano, Frank J, Rebar, Edward J, Huang, Yan, Hickey, Reed, Nath, Anjali K, Meoli, David, Nath, Sameer, Chen, Bingliang, Xu, Lei, Liang, Yuxin, Jamieson, Andrew C, Zhang, Lei, Spratt, S Kaye, Case, Casey C, Wolffe, Alan
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Amino Acid Sequence Angiogenesis Inducing Agents Animals Biomedical and Life Sciences Biomedicine Cancer Research Deoxyribonucleic acid DNA Drug Design Gene Expression Regulation Genetic Therapy Infectious Diseases Metabolic Diseases Mice Models, Animal Molecular Medicine Molecular Sequence Data Neovascularization, Physiologic Neurosciences Protein Engineering - methods Recombinant Proteins Transcription Factors - genetics Transcription Factors - physiology Vascular Endothelial Growth Factor A Zinc Fingers - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!