TrkB levels in the cochlear nucleus after unilateral cochlear ablation: correlations with post-lesion plasticity

Tyrosine kinase B (TrkB) levels in the adult guinea pig cochlear nucleus (CN) were determined from Western blots for up to 60 days after unilateral cochlear ablation (UCA). Compared to TrkB levels on the intact side, those on the lesioned side were elevated in the anteroventral CN (AVCN) at 7 and 60...

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Veröffentlicht in:	Brain research 2002-12, Vol.957 (2), p.366-368
Hauptverfasser:	Suneja, Sanoj K, Potashner, Steven J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cochlea - injuries Cochlea - surgery Cochlear Nerve - injuries Cochlear Nerve - surgery Cochlear nucleus Cochlear Nucleus - cytology Cochlear Nucleus - enzymology Ear and associated structures. Auditory pathways and centers. Hearing. Vocal organ. Phonation. Sound production. Echolocation Functional Laterality - physiology Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Enzymologic - physiology Guinea Pigs Nerve Degeneration - enzymology Nerve Degeneration - physiopathology Nerve Regeneration - physiology Neuronal Plasticity - physiology Neurons, Afferent - cytology Neurons, Afferent - enzymology Plasticity Presynaptic Terminals - enzymology Presynaptic Terminals - ultrastructure Reaction Time - physiology Receptor, trkB - metabolism Receptors, AMPA - metabolism Receptors, Glycine - metabolism Synaptic Transmission - physiology TrkB Up-Regulation - physiology Vertebrates: nervous system and sense organs
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