Continuous measurement of oxygen consumption by pancreatic islets

The rate of oxygen consumption is an important measure of mitochondrial function in all aerobic cells. In pancreatic beta cells, it is linked to the transduction mechanism that mediates glucose-stimulated insulin secretion. However, measurement of oxygen consumption over long periods of time is tech...

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Veröffentlicht in:	Diabetes technology & therapeutics 2002, Vol.4 (5), p.661-672
Hauptverfasser:	Sweet, Ian R, Khalil, Gamal, Wallen, Angela R, Steedman, Mark, Schenkman, Kenneth A, Reems, Jo Anna, Kahn, Steven E, Callis, James B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biosensing Techniques Calibration Cell Membrane - physiology Cell Survival Cells, Cultured Cytochromes - chemistry Cytochromes - metabolism Electrodes In Vitro Techniques Insulin - analysis Islets of Langerhans - chemistry Islets of Langerhans - metabolism Male Oxidation-Reduction Oxygen - blood Oxygen Consumption - physiology Perfusion Rats Rats, Inbred BB
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