Role of CD4+ and CD8+ T cells in the rejection of concordant pancreas xenografts

We studied the ability of CD4 and CD8 T cells to induce rejection of pancreas xenografts in a concordant combination using rat pancreas xenografts as donors and chemically induced diabetic mice as recipients. Lewis rat (2 to 3 weeks old) pancreas xenografts were transplanted into streptozotocin (STZ...

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Veröffentlicht in:	Transplantation 2002-11, Vol.74 (9), p.1236-1241
Hauptverfasser:	YIN, Deng-Ping, MA, Lian-Li, SANKARY, Howard N, JIKUN SHEN, HUASONG ZENG, VARGHESE, Anncy, CHONG, Anita S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences CD4-Positive T-Lymphocytes - physiology CD8-Positive T-Lymphocytes - physiology Diabetes Mellitus, Experimental - surgery Fundamental and applied biological sciences. Psychology Fundamental immunology Graft Rejection - physiopathology Mice Mice, Inbred Strains Pancreas Transplantation Rats Rats, Inbred Lew Tissue, organ and graft immunology Transplantation, Heterologous
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