Chronological changes of the contractile mechanism in prolonged vasospasm after subarachnoid hemorrhage: From protein kinase C to protein tyrosine kinase

Protein kinase C (PKC) plays a role in vasospasm after subarachnoid hemorrhage with a "two-hemorrhage" canine model until Day 7. However, clinical vasospasm continues during the course of 2 weeks. This study sought to clarify whether the contractile property of cerebral arteries might chan...

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Veröffentlicht in:	Neurosurgery 2002-12, Vol.51 (6), p.1468-1476
Hauptverfasser:	KOIDE, Masayo, NISHIZAWA, Shigeru, OHTA, Seiji, YOKOYAMA, Tetsuo, NAMBA, Hiroki, MACDONALD, R. Loch, DODD, Robert L, STEINBERG, Gary K, SELMAN, Warren R, DEMPSEY, Robert J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basilar Artery - diagnostic imaging Basilar Artery - drug effects Basilar Artery - physiopathology Biological and medical sciences Cerebral Angiography Dogs Drug Resistance Female Genistein - pharmacology Isometric Contraction Male Medical sciences Neurology Papaverine - pharmacology Potassium - pharmacology Protein Kinase C - metabolism Protein-Tyrosine Kinases - metabolism Subarachnoid Hemorrhage - complications Time Factors Vascular diseases and vascular malformations of the nervous system Vasoconstriction Vasodilator Agents - pharmacology Vasospasm, Intracranial - diagnostic imaging Vasospasm, Intracranial - enzymology Vasospasm, Intracranial - etiology Vasospasm, Intracranial - physiopathology
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