Successful Treatment of Methicillin-resistant Staphylococcus aureus Keratitis with Topical Ciprofloxacin

Ciprofloxacin is a new quinolone antibiotic with a broad spectrum of activity against most aerobic gram-positive and gram-negative bacteria. Topical ciprofloxacin (3 mg/ml) was used to treat bacterial keratitis caused by methicillin-resistant strains of Staphylococcus aureus in two patients. Both co...

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Veröffentlicht in:Ophthalmology (Rochester, Minn.) Minn.), 1991-11, Vol.98 (11), p.1690-1692
Hauptverfasser: Insler, Michael S., Fish, Larry A., Silbernagel, Jeffrey, Hobden, Jeffery A., O'Callaghan, Richard J., Hill, James M.
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container_end_page 1692
container_issue 11
container_start_page 1690
container_title Ophthalmology (Rochester, Minn.)
container_volume 98
creator Insler, Michael S.
Fish, Larry A.
Silbernagel, Jeffrey
Hobden, Jeffery A.
O'Callaghan, Richard J.
Hill, James M.
description Ciprofloxacin is a new quinolone antibiotic with a broad spectrum of activity against most aerobic gram-positive and gram-negative bacteria. Topical ciprofloxacin (3 mg/ml) was used to treat bacterial keratitis caused by methicillin-resistant strains of Staphylococcus aureus in two patients. Both corneal ulcers had been previously treated with other antibiotics without success. Topical ciprofloxacin was curative in both cases. The authors recommend the use of topical ciprofloxacin for methicillin-resistant S. aureus keratitis.
doi_str_mv 10.1016/S0161-6420(91)32067-0
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ispartof Ophthalmology (Rochester, Minn.), 1991-11, Vol.98 (11), p.1690-1692
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Administration, Topical
Aged
Aged, 80 and over
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Ciprofloxacin - therapeutic use
Corneal Ulcer - drug therapy
Corneal Ulcer - microbiology
Eye Infections, Bacterial - drug therapy
Female
Humans
Male
Medical sciences
Methicillin Resistance
Pharmacology. Drug treatments
Staphylococcal Infections - drug therapy
Staphylococcus aureus - drug effects
Staphylococcus aureus - isolation & purification
Visual Acuity
title Successful Treatment of Methicillin-resistant Staphylococcus aureus Keratitis with Topical Ciprofloxacin
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