Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site (GPS) motif

The calcium-independent receptor of alpha-latrotoxin (CIRL), a neuronal cell surface receptor implicated in the regulation of exocytosis, is a natural chimera of the cell adhesion protein and the G protein-coupled receptor (GPCR). In contrast with canonic GPCRs, CIRL consists of two heterologous non...

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Veröffentlicht in:	The Journal of biological chemistry 2002-11, Vol.277 (48), p.46518-46526
Hauptverfasser:	Krasnoperov, Valery, Lu, Yun, Buryanovsky, Leonid, Neubert, Thomas A, Ichtchenko, Konstantin, Petrenko, Alexander G
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Amino Acid Sequence Animals Base Sequence Cell Adhesion COS Cells DNA Primers GTP-Binding Proteins - metabolism Humans Hydrolysis Membrane Proteins Molecular Sequence Data Protein Processing, Post-Translational Receptors, Cell Surface - chemistry Receptors, Cell Surface - metabolism Receptors, G-Protein-Coupled Receptors, Peptide - chemistry Receptors, Peptide - metabolism Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - metabolism Sequence Homology, Amino Acid Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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