Antidepressant effects on kinase gene expression patterns in rat brain

Multiple kinase pathways determine serotonin transporter (SERT) regulation. We hypothesized a decrease in kinase expression with chronic selective serotonin reuptake inhibitor (SSRI) administration necessary to regulate extracellular serotonin. We studied whole brain kinase mRNA expression on Affyme...

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Veröffentlicht in:	Neuroscience letters 2002-12, Vol.334 (2), p.91-94
Hauptverfasser:	Rausch, J.L., Gillespie, C.F., Fei, Y., Hobby, H.M., Stoming, T., Ganapathy, V., Leibach, F.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressants Antidepressive Agents, Second-Generation - pharmacology Biological and medical sciences Brain - drug effects cAMP-mediated protein kinase Citalopram Citalopram - pharmacology Fluoxetine Fluoxetine - pharmacology Gene Expression Regulation Janus protein kinase kinase Male Medical sciences Neuropharmacology Oligonucleotide Array Sequence Analysis Pharmacology. Drug treatments Phosphofructokinase Phosphofructokinase M Phosphotransferases - drug effects Phosphotransferases - genetics Protein kinase Protein kinase C Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Rats RNA, Messenger - analysis Serotonin Serotonin transporter Serotonin uptake Stress-activated protein kinase Time Factors
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