Differentiation of Engrafted Neuronal-Restricted Precursor Cells Is Inhibited in the Traumatically Injured Spinal Cord

Differentiation of pluripotent neural stem cells engrafted into the adult normal and injured spinal cord is restricted to the glial lineage, suggesting that in vitro induction toward a neuronal lineage prior to transplantation and/or modification of the host environment may be necessary to initiate...

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