Adenovirus Vector-mediated Overexpression of a Truncated Form of the p65 Nuclear Factor κB cDNA in Dendritic Cells Enhances Their Function Resulting in Immune-mediated Suppression of Preexisting Murine Tumors

Purpose: The purpose of this study was to evaluate the effect of the Rel homology domain (RHD) of the transcription factor, nuclear factor κB (NFκB), on proinflammatory gene expression in bone marrow-derived dendritic cells (BMDCs). Experimental Design: We used an adenovirus vector encoding only the...

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