Self epitopes shared between human skeletal myosin and Streptococcus pyogenes M5 protein are targets of immune responses in active juvenile dermatomyositis

Objective To identify self T cell epitopes associated with proinflammatory immune responses and clinically active juvenile dermatomyositis (juvenile DM). The target of our search for relevant epitopes was represented by amino acid sequences shared between human skeletal myosin and Streptococcus pyog...

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Veröffentlicht in:	Arthritis and rheumatism 2002-11, Vol.46 (11), p.3015-3025
Hauptverfasser:	Massa, Margherita, Costouros, Nick, Mazzoli, Federica, De Benedetti, Fabrizio, La Cava, Antonio, Le, Tho, de Kleer, Isme, Ravelli, Angelo, Liotta, Margaret, Roord, Sarah, Berry, Charles, Pachman, Lauren M., Martini, Alberto, Albani, Salvatore
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - immunology Biological and medical sciences Child Cross Reactions Dermatomyositis - immunology Dermatomyositis - therapy Epitopes - immunology Humans Immunotherapy - methods Medical sciences Myosins - immunology Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Streptococcus pyogenes - immunology T-Lymphocytes, Cytotoxic
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