Immunology of Postviral Fatigue Syndrome

Immunology of Postviral Fatigue Syndrome

Postviral fatigue syndrome is associated with persistent infection by a virus. The patient with the condition has failed to eliminate the virus in the usual time. There is little evidence of a deficient immune response by the patient as the explanation for the viral persistence, and it must be assum...

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Veröffentlicht in:British medical bulletin 1991-10, Vol.47 (4), p.886-894
Hauptverfasser: Mowbray, J F, Yousef, G E
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies, Viral - immunology
Biological and medical sciences
Fatigue Syndrome, Chronic - immunology
Humans
Infectious diseases
Interferons - immunology
Interleukin-1 - immunology
Interleukin-2 - immunology
Medical sciences
Tumor Necrosis Factor-alpha - immunology
Viral diseases
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container_title British medical bulletin
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creator Mowbray, J F
Yousef, G E
description Postviral fatigue syndrome is associated with persistent infection by a virus. The patient with the condition has failed to eliminate the virus in the usual time. There is little evidence of a deficient immune response by the patient as the explanation for the viral persistence, and it must be assumed that most of the explanation lies in down-regulation of virus experssion in infected cells. The general symptomatology of postinfectious syndromes may be mediated by cytokines liberated as part of the infection. Part of the syndrome may also be due to local effects of virus infection in muscles or the central nervous system (CNS).
doi_str_mv 10.1093/oxfordjournals.bmb.a072518
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subjects Antibodies, Viral - immunology
Biological and medical sciences
Fatigue Syndrome, Chronic - immunology
Humans
Infectious diseases
Interferons - immunology
Interleukin-1 - immunology
Interleukin-2 - immunology
Medical sciences
Tumor Necrosis Factor-alpha - immunology
Viral diseases
title Immunology of Postviral Fatigue Syndrome
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