Impaired antioxidant status and decreased dietary intake of antioxidants in patients with systemic lupus erythematosus
This study compared plasma antioxidant/oxidant status and the dietary nutrient intake of patients with systemic lupus erythematosus (SLE) to those of healthy controls. The study included 97 consecutive patients with SLE and 97 age- and sex-matched healthy controls. Blood samples from 19 patients and...
Gespeichert in:
| Veröffentlicht in: | Rheumatology international 2002-11, Vol.22 (6), p.238-243 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 243 |
|---|---|
| container_issue | 6 |
| container_start_page | 238 |
| container_title | Rheumatology international |
| container_volume | 22 |
| creator | BAE, Sang-Cheol KIM, Soo-Jin SUNG, Mi-Kyung |
| description | This study compared plasma antioxidant/oxidant status and the dietary nutrient intake of patients with systemic lupus erythematosus (SLE) to those of healthy controls.
The study included 97 consecutive patients with SLE and 97 age- and sex-matched healthy controls. Blood samples from 19 patients and 19 controls were subjected to analyses of plasma concentrations of alpha-tocopherol and malone dialdehyde and the activities of superoxide dismutase and glutathione peroxidase in the plasma. All patients and controls were interviewed using a semiquantitative food-frequency questionnaire.
The plasma alpha-tocopherol concentration was lower in patients, but this difference was not statistically significant. Plasma superoxide dismutase and glutathione peroxidase activities were significantly lower in patients than in controls, and the plasma malone dialdehyde level was significantly higher in patients than in controls. The intake of all major dietary antioxidants, including vitamin A, beta-carotene, and vitamin C, but not retinol, was lower in patients than in controls, but this difference was significant only for vitamin A and beta-carotene.
These results show that plasma antioxidant status is impaired and dietary antioxidant intake is decreased in patients with SLE. |
| doi_str_mv | 10.1007/s00296-002-0241-8 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72675446</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72675446</sourcerecordid><originalsourceid>FETCH-LOGICAL-c354t-7acf0e9dab439e051de6c5f8a5bc7bd7c2958b61068685b54638b5c9016c3c923</originalsourceid><addsrcrecordid>eNpdkUuLFTEQhYMozp2rP8CNNIKza8076aUMPgYG3Ci4C-mkmsnYL1Npx_vvzeVeGHFTlRTfORVyCHnF6DtGqXmPlPJOt7W2lEvW2idkx6QwLdP0x1Oyo8zw1tZyQS4R72m9a02fkwvGJdda8x35fTOtPmWIjZ9LWv6kWHuDxZcN6yg2EUIGjxWICYrPhybNxf-EZhn-lWAdN6svCY7nh1TuGjxggSmFZtzWagb5UO5g8mXBDV-QZ4MfEV6e-558__Tx2_WX9vbr55vrD7dtEEqW1vgwUOii76XogCoWQQc1WK_6YPpoAu-U7TWj2mqreiW1sL0KHWU6iNBxsSdXJ981L782wOKmhAHG0c-wbOgM10bJKtuTN_-B98uW5_o2Z61kwkhJK8ROUMgLYobBrTlN9U8co-6YiDsl4mp1x0ScrZrXZ-OtnyA-Ks4RVODtGfAY_DhkP4eEj1zda0RnxF9RkZXd</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>884137440</pqid></control><display><type>article</type><title>Impaired antioxidant status and decreased dietary intake of antioxidants in patients with systemic lupus erythematosus</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>BAE, Sang-Cheol ; KIM, Soo-Jin ; SUNG, Mi-Kyung</creator><creatorcontrib>BAE, Sang-Cheol ; KIM, Soo-Jin ; SUNG, Mi-Kyung</creatorcontrib><description>This study compared plasma antioxidant/oxidant status and the dietary nutrient intake of patients with systemic lupus erythematosus (SLE) to those of healthy controls.
The study included 97 consecutive patients with SLE and 97 age- and sex-matched healthy controls. Blood samples from 19 patients and 19 controls were subjected to analyses of plasma concentrations of alpha-tocopherol and malone dialdehyde and the activities of superoxide dismutase and glutathione peroxidase in the plasma. All patients and controls were interviewed using a semiquantitative food-frequency questionnaire.
The plasma alpha-tocopherol concentration was lower in patients, but this difference was not statistically significant. Plasma superoxide dismutase and glutathione peroxidase activities were significantly lower in patients than in controls, and the plasma malone dialdehyde level was significantly higher in patients than in controls. The intake of all major dietary antioxidants, including vitamin A, beta-carotene, and vitamin C, but not retinol, was lower in patients than in controls, but this difference was significant only for vitamin A and beta-carotene.
These results show that plasma antioxidant status is impaired and dietary antioxidant intake is decreased in patients with SLE.</description><identifier>ISSN: 0172-8172</identifier><identifier>EISSN: 1437-160X</identifier><identifier>DOI: 10.1007/s00296-002-0241-8</identifier><identifier>PMID: 12426662</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Adult ; alpha-Tocopherol - blood ; Antioxidants ; Antioxidants - metabolism ; Biological and medical sciences ; Diet ; Diet Surveys ; Disability Evaluation ; Female ; Glutathione Peroxidase - blood ; Humans ; Lupus ; Lupus Erythematosus, Systemic - blood ; Lupus Erythematosus, Systemic - physiopathology ; Male ; Malondialdehyde - blood ; Medical sciences ; Plasma ; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis ; Severity of Illness Index ; Superoxide Dismutase - blood ; Surveys and Questionnaires ; Vitamin E</subject><ispartof>Rheumatology international, 2002-11, Vol.22 (6), p.238-243</ispartof><rights>2003 INIST-CNRS</rights><rights>Springer-Verlag 2002</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c354t-7acf0e9dab439e051de6c5f8a5bc7bd7c2958b61068685b54638b5c9016c3c923</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14037397$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12426662$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BAE, Sang-Cheol</creatorcontrib><creatorcontrib>KIM, Soo-Jin</creatorcontrib><creatorcontrib>SUNG, Mi-Kyung</creatorcontrib><title>Impaired antioxidant status and decreased dietary intake of antioxidants in patients with systemic lupus erythematosus</title><title>Rheumatology international</title><addtitle>Rheumatol Int</addtitle><description>This study compared plasma antioxidant/oxidant status and the dietary nutrient intake of patients with systemic lupus erythematosus (SLE) to those of healthy controls.
The study included 97 consecutive patients with SLE and 97 age- and sex-matched healthy controls. Blood samples from 19 patients and 19 controls were subjected to analyses of plasma concentrations of alpha-tocopherol and malone dialdehyde and the activities of superoxide dismutase and glutathione peroxidase in the plasma. All patients and controls were interviewed using a semiquantitative food-frequency questionnaire.
The plasma alpha-tocopherol concentration was lower in patients, but this difference was not statistically significant. Plasma superoxide dismutase and glutathione peroxidase activities were significantly lower in patients than in controls, and the plasma malone dialdehyde level was significantly higher in patients than in controls. The intake of all major dietary antioxidants, including vitamin A, beta-carotene, and vitamin C, but not retinol, was lower in patients than in controls, but this difference was significant only for vitamin A and beta-carotene.
These results show that plasma antioxidant status is impaired and dietary antioxidant intake is decreased in patients with SLE.</description><subject>Adult</subject><subject>alpha-Tocopherol - blood</subject><subject>Antioxidants</subject><subject>Antioxidants - metabolism</subject><subject>Biological and medical sciences</subject><subject>Diet</subject><subject>Diet Surveys</subject><subject>Disability Evaluation</subject><subject>Female</subject><subject>Glutathione Peroxidase - blood</subject><subject>Humans</subject><subject>Lupus</subject><subject>Lupus Erythematosus, Systemic - blood</subject><subject>Lupus Erythematosus, Systemic - physiopathology</subject><subject>Male</subject><subject>Malondialdehyde - blood</subject><subject>Medical sciences</subject><subject>Plasma</subject><subject>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</subject><subject>Severity of Illness Index</subject><subject>Superoxide Dismutase - blood</subject><subject>Surveys and Questionnaires</subject><subject>Vitamin E</subject><issn>0172-8172</issn><issn>1437-160X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkUuLFTEQhYMozp2rP8CNNIKza8076aUMPgYG3Ci4C-mkmsnYL1Npx_vvzeVeGHFTlRTfORVyCHnF6DtGqXmPlPJOt7W2lEvW2idkx6QwLdP0x1Oyo8zw1tZyQS4R72m9a02fkwvGJdda8x35fTOtPmWIjZ9LWv6kWHuDxZcN6yg2EUIGjxWICYrPhybNxf-EZhn-lWAdN6svCY7nh1TuGjxggSmFZtzWagb5UO5g8mXBDV-QZ4MfEV6e-558__Tx2_WX9vbr55vrD7dtEEqW1vgwUOii76XogCoWQQc1WK_6YPpoAu-U7TWj2mqreiW1sL0KHWU6iNBxsSdXJ981L782wOKmhAHG0c-wbOgM10bJKtuTN_-B98uW5_o2Z61kwkhJK8ROUMgLYobBrTlN9U8co-6YiDsl4mp1x0ScrZrXZ-OtnyA-Ks4RVODtGfAY_DhkP4eEj1zda0RnxF9RkZXd</recordid><startdate>20021101</startdate><enddate>20021101</enddate><creator>BAE, Sang-Cheol</creator><creator>KIM, Soo-Jin</creator><creator>SUNG, Mi-Kyung</creator><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20021101</creationdate><title>Impaired antioxidant status and decreased dietary intake of antioxidants in patients with systemic lupus erythematosus</title><author>BAE, Sang-Cheol ; KIM, Soo-Jin ; SUNG, Mi-Kyung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c354t-7acf0e9dab439e051de6c5f8a5bc7bd7c2958b61068685b54638b5c9016c3c923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>alpha-Tocopherol - blood</topic><topic>Antioxidants</topic><topic>Antioxidants - metabolism</topic><topic>Biological and medical sciences</topic><topic>Diet</topic><topic>Diet Surveys</topic><topic>Disability Evaluation</topic><topic>Female</topic><topic>Glutathione Peroxidase - blood</topic><topic>Humans</topic><topic>Lupus</topic><topic>Lupus Erythematosus, Systemic - blood</topic><topic>Lupus Erythematosus, Systemic - physiopathology</topic><topic>Male</topic><topic>Malondialdehyde - blood</topic><topic>Medical sciences</topic><topic>Plasma</topic><topic>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</topic><topic>Severity of Illness Index</topic><topic>Superoxide Dismutase - blood</topic><topic>Surveys and Questionnaires</topic><topic>Vitamin E</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BAE, Sang-Cheol</creatorcontrib><creatorcontrib>KIM, Soo-Jin</creatorcontrib><creatorcontrib>SUNG, Mi-Kyung</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Proquest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Rheumatology international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BAE, Sang-Cheol</au><au>KIM, Soo-Jin</au><au>SUNG, Mi-Kyung</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impaired antioxidant status and decreased dietary intake of antioxidants in patients with systemic lupus erythematosus</atitle><jtitle>Rheumatology international</jtitle><addtitle>Rheumatol Int</addtitle><date>2002-11-01</date><risdate>2002</risdate><volume>22</volume><issue>6</issue><spage>238</spage><epage>243</epage><pages>238-243</pages><issn>0172-8172</issn><eissn>1437-160X</eissn><abstract>This study compared plasma antioxidant/oxidant status and the dietary nutrient intake of patients with systemic lupus erythematosus (SLE) to those of healthy controls.
The study included 97 consecutive patients with SLE and 97 age- and sex-matched healthy controls. Blood samples from 19 patients and 19 controls were subjected to analyses of plasma concentrations of alpha-tocopherol and malone dialdehyde and the activities of superoxide dismutase and glutathione peroxidase in the plasma. All patients and controls were interviewed using a semiquantitative food-frequency questionnaire.
The plasma alpha-tocopherol concentration was lower in patients, but this difference was not statistically significant. Plasma superoxide dismutase and glutathione peroxidase activities were significantly lower in patients than in controls, and the plasma malone dialdehyde level was significantly higher in patients than in controls. The intake of all major dietary antioxidants, including vitamin A, beta-carotene, and vitamin C, but not retinol, was lower in patients than in controls, but this difference was significant only for vitamin A and beta-carotene.
These results show that plasma antioxidant status is impaired and dietary antioxidant intake is decreased in patients with SLE.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>12426662</pmid><doi>10.1007/s00296-002-0241-8</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0172-8172 |
| ispartof | Rheumatology international, 2002-11, Vol.22 (6), p.238-243 |
| issn | 0172-8172 1437-160X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_72675446 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult alpha-Tocopherol - blood Antioxidants Antioxidants - metabolism Biological and medical sciences Diet Diet Surveys Disability Evaluation Female Glutathione Peroxidase - blood Humans Lupus Lupus Erythematosus, Systemic - blood Lupus Erythematosus, Systemic - physiopathology Male Malondialdehyde - blood Medical sciences Plasma Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Severity of Illness Index Superoxide Dismutase - blood Surveys and Questionnaires Vitamin E |
| title | Impaired antioxidant status and decreased dietary intake of antioxidants in patients with systemic lupus erythematosus |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-12T04%3A14%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Impaired%20antioxidant%20status%20and%20decreased%20dietary%20intake%20of%20antioxidants%20in%20patients%20with%20systemic%20lupus%20erythematosus&rft.jtitle=Rheumatology%20international&rft.au=BAE,%20Sang-Cheol&rft.date=2002-11-01&rft.volume=22&rft.issue=6&rft.spage=238&rft.epage=243&rft.pages=238-243&rft.issn=0172-8172&rft.eissn=1437-160X&rft_id=info:doi/10.1007/s00296-002-0241-8&rft_dat=%3Cproquest_cross%3E72675446%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=884137440&rft_id=info:pmid/12426662&rfr_iscdi=true |