Recruitment and regulation of phosphatidylinositol phosphate kinase type 1γ by the FERM domain of talin

Membrane phosphoinositides control a variety of cellular processes through the recruitment and/or regulation of cytosolic proteins 1 , 2 , 3 , 4 . One mechanism ensuring spatial specificity in phosphoinositide signalling is the targeting of enzymes that mediate their metabolism to specific subcellul...

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Veröffentlicht in:	Nature (London) 2002-11, Vol.420 (6911), p.85-89
Hauptverfasser:	Di Paolo, Gilbert, Pellegrini, Lorenzo, Letinic, Kresimir, Cestra, Gianluca, Zoncu, Roberto, Voronov, Sergei, Chang, Sunghoe, Guo, Jun, Wenk, Markus R., De Camilli, Pietro
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Alternative Splicing Animals Biological and medical sciences Brain - enzymology Brain - metabolism Cell Adhesion Cell physiology Cell structures and functions Cytoskeletal Proteins - chemistry Cytoskeletal Proteins - metabolism Cytoskeleton, cytoplasm. Intracellular movements Enzyme Activation Focal Adhesions Fundamental and applied biological sciences. Psychology Humanities and Social Sciences Humans Isoenzymes - chemistry Isoenzymes - metabolism letter Mice Molecular and cellular biology multidisciplinary Phosphatidylinositol 4,5-Diphosphate - metabolism Phosphotransferases (Alcohol Group Acceptor) - chemistry Phosphotransferases (Alcohol Group Acceptor) - metabolism Protein Binding Protein Structure, Tertiary Science Science (multidisciplinary) Signal transduction Synapses - enzymology Synapses - metabolism Talin
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