The Claisen condensation in biology

The mechanism for carbon-carbon bond formation used in the biosynthesis of natural products such as fatty acids and polyketides is a decarboxylating Claisen condensation. The enzymes that catalyze this reaction in various bacterial systems, collectively referred to as condensing enzymes, have been i...

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Veröffentlicht in:	Natural product reports 2002-10, Vol.19 (5), p.581-596
Hauptverfasser:	Heath, Richard J, Rock, Charles O
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites - genetics Decarboxylation Enzyme Inhibitors - pharmacology Enzymes - chemistry Enzymes - genetics Enzymes - metabolism Fatty Acids - biosynthesis Humans Models, Molecular Plants - enzymology
Online-Zugang:	Volltext
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