NBS1 Localizes to γ-H2AX Foci through Interaction with the FHA/BRCT Domain

DNA double-strand breaks represent the most potentially serious damage to a genome; hence, many repair proteins are recruited to nuclear damage sites by as yet poorly characterized sensor mechanisms. Here, we show that NBS1, the gene product defective in Nijmegen breakage syndrome (NBS) [1–3], physi...

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Veröffentlicht in:	Current biology 2002-10, Vol.12 (21), p.1846-1851
Hauptverfasser:	Kobayashi, Junya, Tauchi, Hiroshi, Sakamoto, Shuichi, Nakamura, Asako, Morishima, Ken-ichi, Matsuura, Shinya, Kobayashi, Toshiko, Tamai, Katsuyuki, Tanimoto, Keiji, Komatsu, Kenshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Cycle Proteins - metabolism Cell Line Fluorescent Antibody Technique Forkhead Transcription Factors Histones - metabolism Humans Nuclear Proteins - metabolism Transcription Factors - metabolism
Online-Zugang:	Volltext
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